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Using GRASP-DCE MRI for the Identification of Subtypes of Lung Cancers from Benign Lung Lesions.
Dandan Peng1, Cong Xia1, Yuancheng Wang1, Zhongshuai Zhang2, and Shenghong Ju1
1Zhongda Hospital, Medical School of Southeast University, Nanjing, China, 2SIEMENS Healcare, Shanghai, China
This study is expected to provide information about differentiating of benign from malignant pulmonary lesions with  GRASP-DCE MRI among 33 lung lesions. The results initially indicated that the quantitative DCE parameters could be a useful technique for lung lesions detection.
Figure1.The GRASP DCE-derived quantitative values distribution of malignancy and benignity in lung lesions. The mean values of Ve in Adeno-Ca and benign groups are 0.360±0.167 and 0.428±0.114. (ANOVA, p<0.05)
Figure 3. A 72-year-old male with a 6cm mass in the right upper lobe. This mass was diagnosed as adenocarcinoma IIIb (cT4N2M0). (A): Free-breathing Golden-angle RAdial Sparse Parallel (GRASP)-DCE MRI post-processed image showing mean Ktrans of 0.264 min-1, Kep of 1.769 min-1 and Ve of 0.149. The iAUC value of Time-intensity curve for this mass was 0.125. (B):There were 3 early phases images from top to the bottom after contrast injection showing the mass continuous heterogeneous enhancement.