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Phase-Cycled Balanced Steady-State Free Precession Imaging for Functional Lung Imaging at 1.5 and 3 Tesla
Efe Ilicak1, Jascha Zapp1, Safa Ozdemir1, Lothar R. Schad1, and Frank G. Zöllner1,2
1Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, 2Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
Fourier Decomposition MRI uses bSSFP sequence for assessing pulmonary functions. However, it suffers from banding artefacts. We propose phase-cycled acquisitions for improved robustness. In vivo results from 1.5 T and 3 T scanners are provided to demonstrate the proposed method.
Figure 3: Combined functional maps overlaid on a cross-section shown for 1.5 T (a) and 3 T (b). At 1.5T, both phase-cycled maps provide similar contrast and prominent structures (blue arrows) compared to constant phase maps while phase-cycled perfusion map suffers from overall lower values due to averaging. At 3T, both phase-cycled maps show similar contrast and prominent structures (blue arrows) compared to 1.5T. However, the constant phase is less able to reproduce these structures since it is more prone to field inhomogeneity artefacts (white arrows).
Figure 2: Ventilation and perfusion maps of subgroups at 3 T for constant phase (a) and phase-cycled (b) bSSFP acquisitions. As expected, constant phase acquisition generates similar functional maps throughout the experiment whereas phase-cycled acquisition is able to generate functional maps with different information by changing the RF phase. At 3 T, the perfusion maps with conventional $$$\Delta\phi = \pi$$$ acquisition suffer from field inhomogeneity and are less comprehensive compared to phase-cycled acquisitions.