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Quantitative Evaluation of Self-Gating and nonuniform self-gating for highly irregular respiratory patterns
Patrick Metze1, Tobias Speidel1, Fabian Straubmüller1, and Volker Rasche1,2
1Internal Medicine II, Ulm University Medical Center, Ulm, Germany, 2Core Facility Small Animal Imaging (CF-SANI), Ulm University, Ulm, Germany
Non-uniform self-gating (nuSG) enables lung imaging in highly irregular respiratory patterns and outperforms traditional imaging approaches in terms of image sharpness and quantification of fractional ventilation when compared toreference breath-hold imaging.
Figure 2: Exemplary image quality and the corresponding intensity profiles over the lung-liver interface for all three reconstruction techniques and the same acquisition. In expiration (top row) there is not substantial motion blur of the lung-liver interface, although the k-space gated image appears somewhat washed out. For inspiration, the nuSG reconstruction shows highest motion fidelity, followed by the image-gated reconstruction. The lung-liver interface is clearly blurred in the ksp-gated reconstruction.
Figure 3: Exemplary nuSG reconstructed image (right) and time course for uniform and non-uniform motion along the red intensity profile. The displacement of the lung-liver interface exhibits clearly non-uniform motion for the lower row (e.g. around frame 200 and between frame 500 and 600).