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Motor preparatory inhibition is reflected as a layer dependent suppression in the human primary motor cortex
Yinghua Yu1,2, Ikuhiro Kida1,2, and Nobuhiro Hagura1,2
1Center for Information and Neural Networks, National Institute of Information and Communications Technology, Osaka, Japan, 2Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan
Using sub-millimeter BOLD and blood-volume-sensitive (VASO) fMRI in the human motor cortex, we demonstrated that the motor preparatory inhibition can be observed in the primary motor cortex in a layer dependent manner.
Figure 1 (A) BOLD signal activity maps from a representative participant and MRI data acquisition parameters. (B) Averaged (n = 5) response times for three task conditions. (C) Upper panel; Cortical profiles of VASO and BOLD activity changes in the hand-knob area. Lower panel; Activity changes averaged within superficial and deep layers. Error bars indicate the standard error of means across participants. M, Movement; PM, Prepared Movement.