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Investigating in-vivo function of Zebrin-II stripes of the cerebellum using tactile stimulation and prediction.
Lenno R. P. T. Ruijters1, Nikos Priovoulos1, and Wietske van der Zwaag1
1Spinoza Centre for Neuroimaging, Amsterdam, Netherlands
The digit region in the human cerebellum responds reliably to both prediction and experience of tactile stimuli. With 7T fMRI, we could spatially separate responses to prediction and experience of stimuli, to image zebrin-stripe related function.
Figure 3: Axial and coronal results from all four subject in the Stimulation-NonStimulation conditions, focussing on the cerebellar response region for each subject. A and B performed the task with their right hand, C and D with their left hand. Images show consistent responses in the ipsilateral anterior cerebellum for all subjects and in the posterior lobe of the cerebellum for three (B,C,D).
Figure 4: Axial and coronal results from all four subjects in the Prediction-NoPrediction conditions, focussing on the cerebellar response region in the anterior lobe (White circles). Responses are overlaid on top of the Stimulation response clusters (greyed out). NB that in C, the response is negative. The Prediction responses border the Stimulation responses reliably, but only weakly overlap. These results match our hypothesis. Green circles highlight clusters in the posterior lobe for subject B and D.