A: Tonotopic map of the right hemisphere (red = low frequency, blue = high frequency). Acquired in a blocked design, at 1.2 mm iso. In total 7 frequencies (130 Hz, 200 Hz, 306 Hz, 721 Hz, 1100 Hz, 1700 Hz and 4000 Hz) were used. B: We functionally defined PAC, following the high-low-high gradient on the medial portion of Heschl’s gyrus, see (Moerel et al. 2014). C: Based on the tonotopy, we made selectivity maps to high and low sounds. Difference between center - frequencies is 2.5 octaves. D: Activation map to high and low sounds overlaid on BOLD data. Equi-volume layers sample the cortical depth.

A: Rhythmic 2 Hz sound at a low or high carrier frequency. Participants detected a temporal deviant (red). Target difficulty was modulated between 1 -10 ms temporal shift. B: Hypotheses. Each column depicts a best frequency (BF) region of PAC with a frequency preference to either BF1 or BF2. Stimuli matching BF will elicit larger activation in the respective region than non-BF stimuli. An additional upregulation in superficial layers is expected when detecting a deviant (dotted vs. solid line). We expect this to be spectrally specific to the BF region matching the stimulus frequency.