Junting Zou1, Jilei Zhang2, Zhao Xiance2, Yuanyuan Xie1, Bing Zhang1, and Xiaoli Mai1
1Nanjing Drum Tower Hospital, Nanjing, China, 2Philips Healthcare, Shanghai, China
1Nanjing Drum Tower Hospital, Nanjing, China, 2Philips Healthcare, Shanghai, China
The SPIO-huc-MSCs are traced in vivo for 28 days by T2*WI. By quantifying iron concentration, QSM technology can be used to dynamically trace SPIO labeled stem cells in vivo.
FIG. 4. QSM image of SPIO.Mag: Amplitude map, in which nano-iron oxide is black; QSM: The post-processed susceptibility distribution diagram, in which nano-iron oxide is white. We observed characteristic SPIO signals in the T2* hypointense signal region.
FIG. 5. Trend graphs of T2* values and susceptibility values changing over time.The susceptibility values per unit pixel decrease with time, and the total volume of iron increases with time. The T2* values also show a trend of increasing with time.