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Free Water Eliminated White Matter Tract Integrity of Spinal Cord in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder
Masaaki Hori1,2, Kouhei Kamiya1,2, Akifumi Hagiwara2,3, Kazumasa Yokoyama4, Issei Fukunaga5, Katsuhiro Sano2, Koji Kamagata2, Katsutoshi Murata6, Shohei Fujita2, Christina Andica2, Akihiko Wada2, Julien Cohen-Adad7, and Shigeki Aoki2
1Radiology, Toho University Omori Medical Center, Tokyo, Japan, 2Radiology, Juntendo University School of Medicine, Tokyo, Japan, 3Radiology, David Geffen School of Medicine, Los Angeles, CA, United States, 4Neurology, Juntendo University School of Medicine, Tokyo, Japan, 5Juntendo University School of Medicine, Tokyo, Japan, 6Siemens Japan K.K, Tokyo, Japan, 7NeuroPoly Lab, Polytechnique Montreal, Montréal, QC, Canada
Fractional anisotropy was significant higher in spinal cord white matter in multiple sclerosis patients, compared with Neuromyelitis optica patients using free water eliminated kurtosis-based white matter tract integrity.
Figure1. Representative metric maps of a case with multiple sclerosis (41-year-old woman) and analysis process.
Figure 2. The results of all metrics values of white matter of spinal cords at each spinal level in patients with MS and NMOSD.