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Quantitative Susceptibility Mapping for Mitral Annulus Calcification Detection via Validation of Computed Tomography/Echocardiography
Jiahao Li1,2, Hannah Mitlak3, Lakshmi Nambiar3, Romina Tafreshi3, Jiwon Kim3, Yi Wang1,2, Jonathan W. Weinsaft3, and Pascal Spincemaille2
1Biomedical Engineering, Cornell University, Ithaca, NY, United States, 2Radiology, Weill Cornell Medicine, New York, NY, United States, 3Medicine, Weill Cornell Medicine, New York, NY, United States
Cardiac QSM is able to detect mitral annulus calcification as confirmed by CT and echocardiography.
Figure 1. Gradient echo (GRE), QSM and R2* in representative cases of A) moderate MAC, B) mild MAC, and C) non-calcification. The corresponding computed tomography of each case is shown in the first column as the reference for presence and severity of calcification. The red arrows indicate the location of mitral annular calcification.
Figure 3. Correlation between CT value and susceptibility in calcification regions from MAC patients. Susceptibility detected by thresholding aligned well with CT reference as linear relationship. H.U., Hounsfield unit; ppm, parts per million. Red points: moderate calcification; blue points: mild calcification.