Pawan Kumar1, Uma Sharma1, Rajeev Narang2, and Sujeet Mewar1
1Nuclear Magnetic Resonance and MRI Facility, All India Institute of Medical Sciences, New Delhi, India, 2Cardiology, All India Institute of Medical Sciences, New Delhi, India
1Nuclear Magnetic Resonance and MRI Facility, All India Institute of Medical Sciences, New Delhi, India, 2Cardiology, All India Institute of Medical Sciences, New Delhi, India
Significant differences in the concentration
of metabolites like lactate, pyruvate, choline, acetate and alanine in the
blood plasma of CAD patients compared to healthy controls indicating metabolic
abnormalities related to the development of CAD.
Figure 2: PLS-DA plot showing separation of patients with CAD (Red) from controls (Green).
Figure 1: 1D 1H NMR spectrum of blood plasma of a patient with CAD acquired at 700 MHz.