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Evaluating the Myocardial Diffusion Status in Cardiac Amyloidosis: A Novel Intravoxel Incoherent Motion Diffusion-weighted MR Imaging Study
Mengdi Jiang1, Xianghua Huang2, Guifen Yang3, Weiqiang Dou4, and Yong Shen5
1Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, NanJing, China, 2National Clinical Research Center of Kidney Disease, Jinling Hospital, Medical School of Nanjing University, NanJing, China, 3Department of Nuclear Medical, Jinling Hospital, Medical School of Nanjing University, NanJing, China, 4GE Healthcare,MR Research China, BeiJing, China, 5GE Healthcare,MR Enhanced Application China, BeiJing, China
IVIM parameters  ADCslow and ADCfast were found to be significantly altered by cardiac amyloidosis, allowing to identify amyloidosis specific patterns.   
Figure 4 Typical example of IVIM-derived parameters, strain and LGE for (A) a healthy control and (B) a LGE(+) patient with cardiac amyloidosis. Other abbreviations as in Figure 2&3.
Figure 2 Box plot indicating the distribution of the ADCslow, ADCfast, and F values among the healthy controls and LGE(+) or LGE(-) patients. LGE= late gadolinium enhancement.