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A Framework to extract and visualize the myofiber helix angle locally and globally from the cardiac diffusion tensor images
Mehrzad Tartibi1, Randall Lee2, Christopher Nguyen3, Jaume Coll-Font3,4, Youngho Seo2, and Qizhi Fang2
1DelBeat Inc., Berkeley, CA, United States, 2University of California San Francisco, San Francisco, CA, United States, 3Massachusetts General Hospital, Boston, MA, United States, 4Harvard Medical School, Boston, MA, United States
Developed a method to remove the trabeculae and the ventricle papillary muscles from the segmentation of the DTI images. This tool allows for accurate measurement of the myofiber helix angle. The swine helix angle is linearly varies from the ventricle endocardium to the epicardium.  
The statistical analysis of the myofiber angle for (A) the swine subject (A) and (B) the swine subject (B).
wall thickness and helix angle distribution are shown on a 2D flattened polar plot of swine subject (A). (A) Swine Subject (A) 3D endocardial surface with wall-thickness contour, (B) 2D-flattened wall thickness contour, (C) 2D-flattened helix angle at the subendocardial surface, and (D) 2D-flattened helix angle at the subepicardial surface. White and black curves represent the marking of right ventricle anterior and interior insertion points, respectively.