3696
Numerical Fit of Extrapolated Semisolid Magnetization Transfer Reference Signal (NEMR) for Improved pH-Weighted Imaging of Ischemic Stroke
Xingwang Yong1, Shanshan Lu2, Yi-Cheng Hsu3, Yi Sun3, Dan Wu1, and Yi Zhang1
1Key Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China, 2The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China, 3MR Collaboration, Siemens Healthcare Ltd., Shanghai, China
A novel method was proposed for removing contamination in the CEST signal by the numerical fitting of the extrapolated semisolid magnetization transfer reference signal (NEMR). NEMR yielded substantially better contrast for depicting ischemic stroke lesions than the MTRasym method.
Figure 2. DWI, APTw, APT#, and NOE# images of a representative case using saturation B1 power of 1uT and 1.5uT.
Figure 5. DWI, APTw, APT#, and NOE# images of a representative case at a B1 power of 1uT.