3703
The value of Amide Proton Transfer weighted and Dynamic Contrast-Enhanced imaging in peritumoral edema assisted grading of gliomas
Xinying Ren1, Yujing Li1, Rui Wang1, Tao Wen1, Diaohan Xiong1, Pengfei Wang1, Guangyao Liu1, Jing Zhang1, and Kai Ai2
1Department of Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou, China, 2Philips Healthcare, Xi'an, China
The APT value and the DCE-MRI parameters of Ktrans  of peritumor edema may serve as a potential biomarker assisted grading of gliomas. The former may be more conductive to differentiate grade Ⅱ and grade Ⅲ gliomas.
*Note: Using the one-way ANOVA and spearman’s correlation coefficient for ranked data
Figure 1. ROC curve of APT value and Ktrans value in peritumoral edema between grade Ⅱ and Ⅲ (AUC: 0.971 for APT, 0.714 for Ktrans; 95%CI: 0.89-1.00 for APT, 0.41-1.00 for Ktrans).