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Creation of a four-dimensional numerical phantom for Bloch simulations of water-fat systems
Katsumi Kose1, Ryoichi Kose1, and Yasuhiko Terada2
1MRIsimulations Inc., Tokyo, Japan, 2University of Tsukuba, Tsukuba, Japan
A 4D numerical phantom is indispensable for Bloch simulations of protons in biological tissues with complex distribution of materials. In this study, a 4D phantom was created using an image dataset of an actual biological sample containing water and fat, and the Bloch simulation was performed.  
Fig.3. The four-dimensional numerical phantom for the Bloch simulations of a water-fat system. The 3D water phantom was used for the Bloch simulation in the uniform magnetic field corresponding to -114 Hz resonance frequency. The 3D fat phantom was used for the Bloch simulation in the uniform magnetic field corresponding to +114 Hz resonance frequency. The simulated images were reconstructed after adding the two sets of MR signal obtained for the water and fat phantoms.
Fig.4. (a) The experimentally acquired central cross section of the block bacon for the in-phase and out-of-phase conditions. (b) The simulated central cross section of the block bacon for the in-phase and out-of-phase conditions.