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Uterine cervical adenocarcinomas associated with lobular endocervical glandular hyperplasia: MR imaging manifestations
Mayumi Takeuchi1, Kenji Matsuzaki2, and Masafumi Harada1
1Department of Radiology, Tokushima University, Tokushima, Japan, 2Department of Radiological Technology, Tokushima Bunri University, Sanuki, Japan
LEGH-associated adenocarcinoma (LEGH-AC) may contain solid components with diffusion restriction (DR). LEGH is undifferentiable from LEGH-AC without DR, and gradual contrast-enhancement pattern on DCE-MRI may be suggestive for its benignity.
LEGH-AC: Multicystic mass with solid components exhibiting sponge-like slight high intensity on T2WI, high intensity on DWI with relatively low ADC (1.54 x 10-3mm2/s), maintained high signal intensity on computed DWI (b=1500s/mm2) suggesting diffusion restriction, and rapid & prolonged contrast-enhancement pattern on DCE-MRI.
LEGH: Multicystic mass with solid components exhibiting sponge-like slight high intensity on T2WI, high intensity on DWI with relatively high ADC (2.29 x 10-3mm2/s), decreased signal intensity on computed DWI (b=1500s/mm2) suggesting T2 shine-through effect, and gradual contrast-enhancement pattern on DCE-MRI.