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Combining Volumetric ADC Histogram Analysis with Vesical Imaging Reporting and Data System to Predict the Muscle Invasion of Bladder Cancer
Shichao Li1, Ping Liang1, Yanchun Wang1, Yaqi Shen1, Xuemei Hu1, Daoyu Hu1, Xiaoyan Meng1, and Zhen Li1
1Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Our study demonstrated that both volumetric ADC histogram analysis and VI-RADS can contribute to the distinguishment of muscle invasion for bladder cancer, and the volumetric ADC histogram parameters can provide additional value.
Figure 2. Muscle-invasive papillary urothelial carcinoma in the posterior bladder wall in a 71-year-old-man. a. Axial T2-weighted image; b. Axial DWI images; c. Corresponding diffusion-weighted image reconstruction of ADC values (ADC values are given in units of ×10-3 mm2/s). d. Volumetric ADC histogram shows a large portion of voxels with low ADC values and positive skewness of 2.993 and positive kurtosis of 11.225.
Figure 5. ROC curves of VI-RADS score combined with volumetric ADC histogram parameters