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Head-to-head comparison of PSMA-PET/CT and ferumoxtran-10-enhanced MRI for the diagnosis of lymph node metastases in prostate cancer patients

Melline Gabrielle Maria Schilham¹, Patrik Zamecnik¹, Bas Israel¹, Bastiaan Privé¹, Mark Rijpkema¹, Jelle Barentsz¹, James Nagarajah¹, Martin Gotthardt¹, and Tom Scheenen¹
¹Medical Imaging, Radboudumc, Nijmegen, Netherlands

Nano-MRI identifies significantly more small suspicious lymph nodes compared to PSMA- PET/CT in the same patient.

Size distribution of suspicious lymph nodes as detected by nanoparticle-enhanced MRI (green) and prostate-specific membrane antigen PET/CT (blue).

FIGURE 3. Anatomic distribution of identified suspicious lymph nodes as detected by nanoparticle-enhanced MRI and prostate-specific membrane antigen PET/CT.