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Can texture analysis of T2WI be used to predict extrathyroidal extension in papillary thyroid carcinoma?
Heng Zhang1, Shudong Hu1, Weiqiang Dou2, and Weiyin Vivian Liu2
1Department of Radiology, Affiliated Hospital, Jiangnan University, Wuxi, China, 2GE Healthcare, MR Research, Bejing, China
76 patients with pathologically confirmed papillary thyroid carcinoma (PTC) underwent preoperative thyroid T2-weighted (T2WI) MRI examination in this retrospective study. Using texture analysis for acquired T2WI imaging, entropy was found significantly higher in PTC patients with extrathyroidal extension (ETE) than without ETE, and thus considered an independent index for predicting PTC patients with ETE. With this finding, we therefore consider that preoperative T2WI-based texture features may be valuable for identifying ETE status in PTC patients and may help customize treatment strategies.
Figure 1 A ROI segmentation in a randomly selected case based on sagittal transverse T2WI. (A) Images from a representative PTC patient without ETE (female, 47 years old). (B) Images from a representative PTC patient with ETE (female, 37 years old).
Table 3 Multivariate logistic regression analysis results