3964
Spatial localisation for mapping regional oxygen extraction fraction using parallel transmission saturation pulses at 7 T
Yan Tong1, Peter Jezzard1, Caitlin O'Brien1,2, and William T Clarke1
1Wellcome Centre for Integrative Neuroimaging, FMRIB Division, NDCN, University of Oxford, Oxford, United Kingdom, 2Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
A parallel transmission RF pulse design is presented to measure regional oxygen extraction fraction at 7 T based on the TRUST method. Initial phantom results showed the feasibility of the method, but further in vivo studies are needed for the validation of this approach.
EPI images acquired on an oil phantom with a pulse voltage of 180V and different numbers of repetitions of the saturation module. The left, middle, and right columns show 1, 2, and 3 repetitions of the saturation module, respectively. The bottom, middle, top rows show images acquired at the bottom, in the middle, and at the top of the inversion slab, respectively.
Schematic of the labelling strategies for the proposed method. A cylindrical ROI is chosen.