4002
Artifact Evaluation of Quantitative Susceptibility Mapping Reconstructions Using Mask Parameter Perturbation
Priya S Balasubramanian1,2, Alexandra Grace Roberts1,2, Pascal Spincemaille2, Thanh Nguyen 2, and Yi Wang1,2
1Cornell University, New York City, NY, United States, 2Weill Cornell Medical College, New York City, NY, United States
A method of perturbing tissue mask is proposed to map artifacts associated with strong susceptibility sources recognized as a major cause of errors in QSM algorithms and is validated in a numerical phantom of a known susceptibility distribution and in vivo COSMOS reference data. 
Figure 1. PDM is the absolute value of the difference between the full mask reconstruction, and the perturbed, 5mm eroded mask reconstruction. Artifacts shown with yellow arrows.
Figure 4 a) QSM and PDM in a hemorrhage case. Shown are MEDI, MEDI SMV, TFI, TFIR, and the field uncertainty. b) shadow score and PDM average for each method for 11 cases. Both scores decrease together as visual image artifacts decrease in a).