4077
Associations between Bone Turnover Biomarkers and MR-based Knee composition and WORMS scores:cross-sectional
WANG BIN1, TAN HUI1, HE Taiping1, YU Nan1, and WANG Shaoyu2
1Shaanxi University of Chinese Medicine, SHAANXI, China, 2Siemens Healthineers, shanghai, China
We found that bone markers were weakly correlated with T2 values of cartilage and meniscus.Interestingly, we found that bone formation markers (BAP) had a well correlation with osteophyte scores in WORMS, and abnormal changes of bone formation markers may be related to osteophytes.
Figure 2. The correlation between BAP and Osteophyte WORMS scores was illustrated by correlation fitting scatter plots. Partial correlations are listed with adjustments for age, gender, BMI, KL grade.
Figure 1 a and b: A 51-year-old famale with OA, right knee K-L 3, PD-weighted image(a) and T2 Mapping image(b), Meniscus lateral anterior is normal and the values of T2 is 24.72 ms, osteocalcin: 19.66 ng/ml, tP1NP: 64.94 ng/ml, β-CTX: 691 pg/ml. c and d: A 71-year-old famale with OA, right knee K-L 2, PD-weighted image(c) and T2 Mapping image(d), Meniscus lateral anterior is degeneration and the values of T2 is 28.44 ms, osteocalcin: 13.51 ng/ml, tP1NP: 46.25 ng/ml, β-CTX: 224 pg/ml.