4095
Optimal 2D-ROI Method to Measure Apparent Diffusion Coefficient of Lesions in Prostate MRI
Hiroaki Takahashi1, Kotaro Yoshida2, Akira Kawashima3, Num Ju Lee4, Adam T Froemming4, Daniel A Adamo4, Ashish Khandelwal4, Candice W Bolan5, Matthew T Heller6, Robert P Hartman4, Bohyun Kim4, Kenneth A Philbrick4, Rickey E Carter5, Lance A Mynderse4, Mitchell R Humphreys6, and Naoki Takahashi4
1Department of Radiology, Mayo Clinic, Rochester, Rochester, MN, United States, 2Department of Diagnostic Radiology, Kanazawa University School of Medical Science, Kanazawa, Japan, 3Department of Radiology, Mayo Clinic, Arizona, Scottsdale, AZ, United States, 4Mayo Clinic, Rochester, Rochester, MN, United States, 5Mayo Clinic, Florida, Jacksonville, FL, United States, 6Mayo Clinic, Arizona, Scottsdale, AZ, United States
The optimal method for measuring ADC values for differentiating csPCa and non-csPCa on prostate MRI are 2D-ROI placed on the lowest ADC area using 6-8 mm2.
Fig.1. A dot plot of AUC values of receiver operating characteristics in differentiation of presence or absence of clinically significant prostate cancer for 2D-small-ROI with different area
Fig.5. Bland-Altman plots of ADC values measured by using 3D-whole-lesion-ROI method (10th percentile). 95% limits of agreement among the readers on was +/-112.