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T2-Weighted MRI-Derived Texture Features in Characterization of Prostate Cancer
Dharmesh Singh1, Virendra Kumar2, Chandan J Das3, Anup Singh1, and Amit Mehndiratta1
1Centre for Biomedical Engineering (CBME), Indian Institute of Technology (IIT) Delhi, New Delhi, India, 2Department of NMR, All India Institute of Medical Sciences (AIIMS) Delhi, New Delhi, India, 3Department of Radiology, All India Institute of Medical Sciences (AIIMS) Delhi, New Delhi, India
Texture analysis based machine learning approaches are presented in characterization of PI-RADS v2 grades of prostate cancer using T2WI. The use of texture features extracted from T2WI, DWI and ADC improve the accuracy of prostate cancer characterization by almost 23% compared to T2WI alone
Figure 1: ROC plot for a) LG vs. IG vs. HG and b) PI-RADS grade 4 vs. grade 5 classification using T2WI. Red curves stand for the performance of linear SVM, green curves for Gaussian SVM and blue curves for KNN classifier. ROC = Receiver-operating characteristics, CV = cross-validation, SVM = Support vector machine, KNN = K-nearest neighbour, DWI = Diffusion-weighted imaging, ADC = Apparent diffusion coefficient
Table 1: Features extracted from different texture models. FOS = First order statistics, GLCM = Gray level co-occurrence matrix, GLRLM = Gray level run length matrix, SFM = Statistical feature matrix, LTEM = Law's texture energy measures