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Effect of Small Vessel Disease Burden on Collateral Perfusion in Symptomatic Large Vessel Stenosis or Occlusion
Liu-xian Wang1, Dong-shan Han1, Jin-hao Lyu1, and Xin Lou1
1the First Medical Center, Chinese PLA General Hospital, Beijing, China
In patients with ICA/MCA severe stenosis/occlusion, those with SVD were older and showed higher incidence of diabetes mellitus. Total SVD burden were not associated with collateral circulation. Perivascular space could affect collaterals.
Figure 2. Descriptive figures of the change of collateral perfusion and total SVD score along with the interval from symptom onset to imaging (A). Collateral perfusion decreased with the increase of total SVD score (B). Collateral perfusion was defined as (CBF 2.5s minus CBF 1.5s) at lesion side minus (CBF 2.5s minus CBF 1.5s) at normal side. SVD, small vessel disease.
Figure 3. Cross-sectional correlates of collateral perfusion in symptomatic ICA/MCA severe stenosis or occlusion. ICA, internal carotid artery; MCA, middle cerebral artery; SVD, small vessel disease. a, interval from symptom onset to imaging (days); b, total SVD score. * p < 0.05.