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T2 Quantification in Brain Using Three Dimensional Fast Spin Echo Imaging with Long Echo Trains
Jeff Snyder1 and Alan H Wilman1
1Biomedical Engineering, University of Alberta, Edmonton, AB, Canada
A 3D FSE method using long echo trains is proposed for quantification of T2 in brain with mapping based on Bloch equation and Echo Phase Graph (EPG) simulations.  Echo train lengths of 96 and 192 were investigated (total scan times of 8:12 and 2:38) at 3 T, with isotropic resolutions of 0.9 and 1.3 mm3.
T2 maps for the ETL = 96 (left) and ETL = 192 (right) variable flip angle trains computed from the two echo times of 6 and 132 ms. Noise is more visible in the 192 case. Note that the slice for the 192 case is slightly offset from the 96 case due to the difference in resolution (0.9 mm3 vs 1.3 mm3)
Images acquired using the proposed echo trains (left four images – 96, and right four – 192). The top row are all images at TE = 6 ms, and the bottom is at TE = 132 ms. Axial and sagittal views are shown for each combination of TE and train length.