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Reduced-FOV 3D MR-ARFI with a joint reconstruction for localizing the focused ultrasound beam in neuromodulation
Huiwen Luo1,2, Michelle K. Sigona1,2, Li Min Chen2,3, Charles F. Caskey2,3, and William A. Grissom1,2,3
1Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, 2Vanderbilt University Institute of Imaging Science, Nashville, TN, United States, 3Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States
MR-ARFI can encode the ultrasound-induced displacements into the phase of an MR image. A two-minute reduced-FOV 3D MR-ARFI scan with a joint image reconstruction method at 3 Tesla was demonstrated to image and localize the entire focus in FUS neuromodulation with a low FUS duty-cycle of 0.85%.
Figure 2. (a) 3D MR-ARFI sequence overview; (b) The proposed k-space undersampling scheme.

Figure 4. Representative reconstructed magnitude images (FUS-ON, positive MEGs) (a) and corresponding ARF displacement maps (b).