Mira Liu1, Yong Jeong1, Gregory Christoforidis1, Niloufar Saadat2, Steven Roth3, Marek Niekrasz1, and Timothy Carroll1
1The University of Chicago, Chicago, IL, United States, 2Northwestern University, Chicago, IL, United States, 3University of Illinois at Chicago, Chicago, IL, United States
1The University of Chicago, Chicago, IL, United States, 2Northwestern University, Chicago, IL, United States, 3University of Illinois at Chicago, Chicago, IL, United States
A retrospective validation study of quantitative intravoxel incoherent motion (IVIM) in a canine model found excellent agreement of IVIM and reference standard perfusion and diffusion values over a range of physiologic conditions: normocapnia, hypercapnia, and post-occlusion.
Figure 1: Shown on the left are quantitative DSC CBF (A,B,C) and quantitative IVIM perfusion (D,E,F) images at normocapnia, hypercapnia, and post-occlusion. On the right is a standard ADC map (G) compared to IVIM diffusion coefficient image (H) post-occlusion.
Figure 2: Correlations of
quantitative IVIM perfusion and DSC qCBF to neutron-capture microspheres at normocapnia,
hypercapnia, and post-occlusion hemispherically. The
correlation suggests comparable agreement between IVIM and neutron-capture
microspheres as standard quantitative DSC CBF.
