Shuai Yang1, Jiuqing Guo1, Lirong Ouyang1, and Weiyin Vivian Liu2
1Department of Radiology, Xiangya Hospital, Central South University, Changsha, China, 2MR Research, GE Healthcare, Beijing, China
1Department of Radiology, Xiangya Hospital, Central South University, Changsha, China, 2MR Research, GE Healthcare, Beijing, China
Our study was the first
application of whole-brain voxel-wise comparisons of IVIM-derived normalized Ds and f values to show physiological alterations in cognition
and emotion-related brain of patients with asymptomatic carotid vulnerable
plaque.
(a) Increased Ds
values at left median cingulate and paracingulate gyrus (DCG.L), posterior cingulate gyrus (PCG.L)
and left precuneus gyrus (PCUN.L) (cluster size = 156), left middle frontal
gyrus (MFG.L), orbital middle frontal gyrus (ORBmid.L) and superior frontal
gyrus (SFG.L) (cluster size = 165) (p ＜0.05,
FWE correction). (b) Decreased Ds values at right middle temporal gyrus (MTG.R),
inferior temporal gyrus (ITG.R)(cluster size = 116)(p ＜0.05, FWE correction). (c) Decreased f values at MTG.R,ITG.R(cluster size = 85) (p ＜0.05, FWE correction).