ISMRM & SMRT Annual Meeting • 15-20 May 2021

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Weekend Course

Standardized & Quantitative Assessment in Body Imaging

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Standardized & Quantitative Assessment in Body Imaging
Weekend Course
ORGANIZERS: Daniel Margolis, Johannes Heverhagen, Hero Hussain, Masako Kataoka
Sunday, 16 May 2021
Concurrent 1 13:00 -  13:45 Moderators: 
: Mustafa Shadi Bashir
: Silvia Chang & Evis Sala
Skill Level: Basic to Advanced
Session Number: WE-17
Parent Session: Standardized & Quantitative Assessment in Body Imaging

Session Number: WE-17

This course will cover various techniques in diffuse liver disease in the first half and new standardized assessment and reporting methods in the kidney, bladder, and ovary.

Target Audience
Clinicians in practice.

Educational Objectives
As a result of attending this course, participants should be able to:
- Select the appropriate technique for liver iron quantification;
- Asses liver steatosis; and
- Evaluate liver fibrosis.

- Discriminate between muscle-invasive and non-muscle invasive bladder cancer;
- Assess the neoplastic risk of ovarian masses; and
- Describe renal cysts using standardized criteria.

  Liver: Iron Quantification
Suraj Serai
Serial surveillance of liver iron concentration (LIC) provides guidance for chelation therapy in patients with iron overload. The diagnosis of iron overload traditionally relies on core liver biopsy, which is limited by invasiveness, sampling error, cost and general poor acceptance by patients and their family. Thus noninvasive diagnostic methods such as MRI are highly attractive for quantification of liver iron concentration (LIC). In this talk, we discuss and review the MRI based quantification methods of LIC.
    Liver: Fibrosis Quantification
Verena Obmann
Plenty of etiologies of diffuse liver disease eventually result in liver fibrosis. Liver fibrosis is exceedingly common worldwide prompting the clinical need for objective noninvasive methods for disease characterization as an alternative or complement to gold-standard liver biopsy. The learning objectives of this educational session are •      To summarize qualitative imaging findings of liver fibrosis in US, CT and MRI •      To know the advantages and drawbacks of each modality •      To learn how to report the presence of liver fibrosis
    Liver: Fat Quantification
S. Sendhil Velan
This presentation will cover the MRI/MRS-based techniques for the quantification of liver fat.   Specifically, this presentation will include relevant MRI/MRS techniques, types of pulse sequences utilized in a clinical setting, challenges, and finally, the state of the art of development and validation of MRI-based approaches for quantification of liver fat. 
  Case Discussion: Liver
Mustafa Shadi Bashir
This talk will discuss the use of MRI-based quantitative biomarkers in the care of patients with liver diseases.
  Bladder: VI-RADS
Valeria Panebianco
The purpose of the talk is to describe the newly developed VI-RADS scoring system aimed at standardization of MRI acquisition, interpretation, and reporting for urinary bladder cancer (BCa). An insight will be given on the BCa diagnostic issues, MRI applications for BCa local staging with assessment of muscle invasiveness, and clinical implications of the score for the disease management. In addition, future prospective of the score applicability will be provided, on its role in patients’ stratification for therapeutic planning, disease surveillance, and for the evaluation of response to therapy. Finally, a clinical series with multiple-choice questions will be shown.
    Case Discussion: Genitourinary
Caroline Reinhold
    Kidney: Bosniak
Matthew Davenport
Bosniak v.2019 is a classification of cystic renal masses that formally incorporates MRI, provides verbose specific definitions for imaging terms, and expands the number of masses to which the historic Bosniak classification applies. The intent of the classification update was to improve specificity for malignancy and improve inter-rater agreement, with the goal of reducing the harms of overdiagnosis and overtreatment.
  Ovary: O-RADS
Isabelle Thomassin-Naggara
This lecture will present O-RADS MR score which was developed to predict malignancy of adnexal masses. This score is an accurate five level categories score that demonstrates a sensitivity and specificity higher than 90% and a good reproducibility (Kappa >0.8). In a multicentric european large validation cohort, only 2 borderline and no invasive cancer were quoted O-RADS MR score 2 (NPV = 98%). This score is mainly based on the analysis of solid tissue using morphological and functional criteria including T2W signal, DW signal and the analysis of time intensity curve on DCE MR sequence.

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