ISMRM25 - Focusing on the Brain: Advancing Quantitative Imaging Techniques

ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

Focusing on the Brain: Advancing Quantitative Imaging Techniques

Digital Poster

Acquisition & Reconstruction

Monday, 12 May 2025

Exhibition Hall

13:45 - 14:45

Session Number: D-04

No CME/CE Credit

		Computer Number: 33 1690. Sharing GRAPPA calibration regions to accelerate quantitative imaging with phase-cycled bSSFP View Presentation Video B. Acikgoz, Y. Moerlen, N. Plähn, E. Peper, P. Radojewski, J. Bastiaansen Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland Impact: Shared calibration region data across repeated acquisitions in quantitative parametric mapping sequences, significantly accelerates quantitative imaging without compromising image quality.
		Computer Number: 34 1691. Resolving partial-volume effects in the brain with multidimensional T1xT2 MRI View Presentation Video N. Priovoulos, H. Liu, D. Benjamini, A. Howard, A. Hess, K. Miller University of Oxford, Oxford, United Kingdom Impact: Resolution limits mean that multiple tissue types are frequently captured within a single MRI voxel. We demonstrate the ability to separate these compartments with 2D-T1xT2 approaches. Measuring multi-dimensional spectra may enable better modelling of the biological sources of MRI contrasts.
		Computer Number: 35 1692. B1 Correction of MRSI Data Using Unsuppressed Water Signals View Presentation Video Y. Zhao, Y. Li, R. Guo, W. Jin, B. Sutton, Z. Meng, C. Xu, W. Zhang, Y. Li, Z-P Liang University of Illinois at Urbana-Champaign, Champaign, United States Impact: The proposed method enables quantitative metabolite concentration estimation, which is robust even in pathological tissues. This method is expected to enhance the accuracy, robustness and reproducibility of MRSI technologies.
		Computer Number: 36 1693. Exercise modulates brain pulsatility: Insights from q-aMRI and MRI-based flow methods View Presentation Video J. Wright, E. Clarkson, H. Kumar, I. Terem, A. Sharifzadeh-Kermani, J. McGeown, E. Maunder, P. Condron, G. Maso-Talou, D. Dubowitz, M. Scadeng, S-J Guild, V. Shim, S. Holdsworth, E. Kwon Mātai Medical Research Institute, Gisborne, New Zealand Impact: This study demonstrates exercise has a physiological effect on fluid flow and brain displacement. It highlights q-aMRI’s potential diagnostic applications, as intracranical dynamics coupling could serve as a potential biomarker of abnormality, especially in intracranial pressure and fluid-related disorders.
		Computer Number: 37 1694. Quantitative T2 and T1 brain mapping based on two fast 3D GRE scans with single and dual steady-states – a robustness study of human imaging at 7T MRI View Presentation Video D. Yacobi, R. Schmidt Weizmann Institute of Science, Rehovot, Israel Impact: This study introduces a method based on fast dual-steady-state GRE scan for 7T MRI that simultaneously estimate T2, T1, and B1. The robustness of the method in-vivo was assessed.
		Computer Number: 38 1695. Measuring cerebrovascular reactivity: a comparison of Gradient-Echo and Spin-Echo BOLD with Arterial Spin Labelling View Presentation Video S. Pomante, F. Fasano, D. Di Censo, S. Censi, F. Graziano, M. Carriero, E. Bliakharskaia, A. Caporale, E. Biondetti, M. Germuska, R. Wise, A. M. Chiarelli University "G. D'Annunzio" of Chieti-Pescara, Chieti, Italy Impact: SE BOLD-fMRI may deliver a marker of CVR that resembles the physiological (CBF) CVR more closely than CVR based on GE BOLD, with the advantage of high signal-to-noise ratio compared to ASL.
		Computer Number: 39 1696. Rapid Mapping of Myelin Fraction Using Interleaved Multi-Echo UTE Acquisitions J. Athertya, J. Lo, J. Wang, S. H. Shin, A. Suprana, E. Chang, Y. Ma, J. Du Department of Radiology, UCSD, San Diego, United States Impact: The interleaved multi-echo UTE acquisition scheme allows rapid estimation of myelin fraction, which may be a useful biomarker to assess demyelination in various neurodegenerative conditions.
		Computer Number: 40 1697. Dependency on Tissue Anisotropy and White Matter Fiber Orientation of Phase-Cycled bSSFP Relaxometry at 3 Tesla View Presentation Video H. Tesh, F. Birk, S. Klinkowski, S. Brodt, K. Scheffler, R. Heule Max Planck Institute for Biological Cybernetics, Tuebingen, Germany Impact: Relaxation parameters and frequency profile asymmetries derived from pc-bSSFP demonstrated a distinct sensitivity to brain tissue microstructure, with a dependency on white matter fiber orientation and fractional anisotropy.
		Computer Number: 41 1698. Correlation between clot RBC content and susceptibility measurements on QSM: an investigation using ex vivo clot analogs View Presentation Video H. Ishimaru, Y. Morofuji, M. Morikawa, A. Ishiyama, C. Somagawa, T. Nakano, Y. Tasaki, S. Miyazaki, R. Toya Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan Impact: A strong positive linear correlation was observed between the susceptibility values of clots measured on QSM and RBC content. By measuring the susceptibility value of clots on QSM, it is possible to estimate the RBC content in the clots.
		Computer Number: 42 1699. MEGA-PRESS Study of Neurotransmitter Changes and Lateralization in the DLPFC in rTMS Treatment for First-Episode Adolescent Depression L. Ma, J. Zhang, Y. Xiong Lanzhou University Second Hospital, LanZhou, China Impact: 3-T ¹H-MRS can be used to measure the changes of GABA and Glx concentrations in patients with depression before and after rTMS treatment, which provides a theoretical basis for exploring the occurrence and treatment mechanism of depression.
		Computer Number: 43 1700. Fast and Reproducible 3D T1ρ Mapping Using Unpaired Phase Cycling and Optimal Sampling of Spin-Lock Times View Presentation Video S. P. Jogi, Q. Peng, R. Jafari, R. Otazo, C. Wu Memorial Sloan Kettering Cancer Center, New York, United States Impact: 3D T1ρ imaging, utilizing optimal spin-lock time (TSL) sampling in combination with unpaired MAPSS, enables rapid and highly reproducible T1ρ measurements. This advancement facilitates longitudinal studies, such as assessing treatment response in radiotherapy.
		Computer Number: 44 1701. Simultaneous 1H/23Na MRF in healthy brain aging: Preliminary data View Presentation Video A. Adlung, Z. Pursel, B. Busi, G. Rodriguez, J. Coresh, G. Madelin New York University Grossman School of Medicine, New York, United States Impact: Quantitative sodium imaging in the brain can be of high interest for investigating healthy aging. Simultaneous ¹H/²³Na MRF enables quantification of sodium and proton MR parameters. This study provides insights on age-dependent changes in MR parameters.
		Computer Number: 45 1702. Clinical evaluation of STrategically Acquired Gradient Echo (STAGE) multi-modal quantitative neuroimaging View Presentation Video Y. Liu, N. He, H. Li, B. Wu, X. Wang, Y. Zhang, S. Ju, F. Yan, E. Haacke Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Impact: Multimodal imaging offers the potential to enhance clinical diagnosis especially for the detection of venous abnormalities and blood products such as microbleeds that cannot be detected with conventional clinical spin echo imaging.
		Computer Number: 46 1703. Relaxometry to get the right values, or getting the right data for the patient: a false dilemma View Presentation Video M. Naeyaert, P. Van Schuerbeek, M. Roose, T. Janssens, H. Raeymaekers Universitair Ziekenhuis Brussel, Jette, Belgium Impact: Currently no simultaneous T1-T2-relaxometry technique exists which is both accurate in phantoms and integrated in the clinic. Clinical usefulness, advanced physical system models, and high-quality phantoms should all be integrated into the development of quantitative relaxometry techniques to achieve this.
		Computer Number: 47 1704. Improved Resolution and Precision of whole-brain multi-parametric qMRI using Deep Learning Denoising and Super-Resolution Reconstruction View Presentation Video H. Do, D. Berkeley, P. Kokeny, S. Sethi, M. Fawaz, K. Ghassaban, W. AlGhuraibawi, B. Tymkiw, J. Ciliberto, K. Holzberger, M. Kadbi, J. Backstrom, K. Berger Canon Medical Systems USA, Inc., Tustin, United States Impact: High-resolution and high-SNR whole-brain qMRI can be acquired within 5-6min using acceleration and DLR. qMRI’s qualitative maps and quantitative weightings may be used for comprehensive evaluation of pathology and longitudinal follow-up.
		Computer Number: 48 1705. R2* bias correction in brain multi-echo GRE data View Presentation Video J. Choi, B. Moon, J. Youn, K. Min, C. Oh, J. Kim, T. Kim, J. Lee Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of Impact: Our method enhances accuracy of R2* mapping by utilizing an iterative approach which excludes the later echoes with unreliable signals. By identifying and masking out regions where correction is ineffective, the approach improves the precision of R2* values.

Similar Session(s)