ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

ISMRM & ISMRT 2025 Annual Meeting & Exhibition

Digital Poster

Pulse Sequence Design & Acceleration Methods for Quantitative MRI

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Pulse Sequence Design & Acceleration Methods for Quantitative MRI
Digital Poster
Acquisition & Reconstruction
Tuesday, 13 May 2025
Exhibition Hall
13:30 -  14:30
Session Number: D-08
No CME/CE Credit

 
Computer Number: 1
2578. A Generalizable Pipeline for MRI Sequence Design Using Bayesian Optimization
X. Wang, L. Wang, C. Liu, Z. Wang, Y. Wang, A. Gossard, Y. Ni, W. Liao, Y. Pu, J. Qu, P. Wang, Z. Li, P. Cao, J. Cai, T. Li
The Hong Kong Polytechnic University, Hong Kong, Hong Kong
Impact: This novel, generalizable pipeline enables the development of optimized, tailored imaging protocols to address diverse clinical needs across various MR applications. It holds the potential to integrate advanced imaging techniques into routine practice, enhancing both diagnostic and research efficiency.
 
 
Computer Number: 2
2579. Towards direct non-invasive detection of cardiac biomagnetism via balanced Rotary Excitation
P. Albertova, M. Gram, M. Blaimer, P. Jakob, P. Nordbeck
University Hospital Würzburg, Würzburg, Germany
Impact: Rotary Excitation (REX)-based field detection provides high sensitivity to pulsed-magnetic fields and is therefore a promising approach for imaging of cardiac biomagnetism. Advancing the REX sequence to reduce sensitivity to B0 inhomogeneities is essential for its application in vivo.
 
Computer Number: 3
2580. Parallel Imaging Using Virtual Conjugate Coils and Spatial Nulling Maps (VCC-SNMs)
J. Hu, Y. Zhao, V. Lau, S. Su, Y. Ding, J. Zhang, C. Man, A. Leong, F. Chen, E. Wu
The University of Hong Kong, Hong Kong, China
Impact: A VCC-SNMs method leveraging the priori knowledge of the image phase constraint was successfully implemented for efficient and robust parallel imaging reconstruction with reduced noise amplification.  
 
Computer Number: 4
2581. Simultaneous T1MPRAGE, FGATIR and NM acquisition of whole brain at 3T
C. H. Moon, D. Kim
University of Pittsburgh, Pittsburgh, United States
Impact: The advantages of new sequence could be beneficial for pre-surgical planning for accurate targeting a subnuclei, and NM measurement in Parkinson's or bipolar disease study, by providing whole brain anatomy, midbrain subnuclei and SN internal differentiation.
 
Computer Number: 5
2582. Silent 3D MRSI at Ultrasonic gradient speeds using a dual-axis head insert gradient at 7T
T. Roos, E. Versteeg, M. Bensink, K. Min Nam, M. McGrory, M. Gosselink, H. Hoogduin, D. Welting, B. de Witte, M. Wienke, W. Schuth, T. Delicaat, M. Borgo, J. van Straalen, M. Heintges, D. Klomp, J. C.W. Siero, J. Wijnen
University Medical Center Utrecht, Utrecht, Netherlands
Impact: Ultrasonic encoding offers a paradigm shift in MRSI, bringing resolutions and scan times closer to imaging techniques. All without the typical trade-offs: preserving spectral bandwidth, while maintaining patient comfort by lacking gradient noise - paving the way for practical, high-resolution MRSI.
 
Computer Number: 6
2583. Improved spatial resolution for Looping Star fMRI using UNFOLD
D. Frey, H. Xiang, J. Fessler, D. Noll
University of Michigan, Ann Arbor, United States
Impact: The results of this work will improve spatial resolution Looping Star fMRI studies with high undersampling rates.
 
Computer Number: 7
2584. Improved Brain Tumor Visualization with 3T Stack-of-Stars Echo Unbalanced T1 Relaxation-Enhanced Steady-State MRI – A Two Center Clinical Study
A. Tóth, R. Edelman, J. Chetta, J. Joyce, J. Eernisse, R. Zi, K. Block, M. Spampinato, A. Varga-Szemes
Medical University of South Carolina, Charleston, United States
Impact: This study highlights the SOS echo-uT1RESS technique's potential to significantly improve visualization and characterization of brain lesions. It offers consistent dark-blood effect and improved lesion conspicuity, while maintaining high image quality and motion robustness, with promising implications for clinical practice.
 
Computer Number: 8
2585. Sequence-agnostic FOV Positioning in Pulseq for Cross-Platform Imaging
M. Shafiekhani, B. Wilhelm-Feldbusch, Q. Chen, M. Zaitsev
University Medical Center Freiburg, Freiburg im Breisgau, Germany
Impact: The universal FOV positioning method implemented in Pulseq supports   off-center imaging on various MRI systems, including those that are currently hardware limited in this regard. Among those are in particular  experimental ultra-low field systems and  non-proton imaging on whole-body MRI.
 
Computer Number: 9
2586. Vendor-Independent Pulseq Lung-Optimized Spoiled Gradient Echo Sequence for Phase-resolved functional Lung (PREFUL) MRI
S. Lüdiger, F. Klimes, M. Speth, M. Wernz, R. Müller, F. Wacker, J. Vogel-Claussen, A. Voskrebenzev
Hannover Medical School, Hannover, Germany
Impact: The demonstrated sequence can be easily shared between centers to homogenize the data acquisition for functional lung imaging with PREFUL and similar methods. The reduction of sequence-related variability, may lead to substantial improvement of reproducibility and comparability between centers.
 
Computer Number: 10
2587. Self-Gated Inversion Recovery Prepared Ultrashort Echo Time Sequence for Improved Direct Myelin Imaging
J. Park, S. Sedaghat, Y. Jung, E. Fu, K. Oguz, H. Jang
University of California, Davis, Sacramento, United States
Impact: The proposed technique may provide a critical tool for assessing demyelination and remyelination in various neurological disorders, including multiple sclerosis, Alzheimer’s disease, traumatic brain injury, and epilepsy, with reduced sensitivity to intra-scan motion.
 
Computer Number: 11
2588. Comprehensive Assessment of Nonuniform Image Quality: Replication and Application to Metal Imaging at 0.55T
A. Sanson Leon, A. Toews, B. Barlas, B. Hargreaves, K. Nayak
University of Southern California, Los Angeles, United States
Impact: We demonstrate successful replication of the original methods paper, utilizing conventional 3D printing, a gyroid lattice phantom, and a THA phantom with a cobalt-chromium head, for the application to MRI near metallic implants at 0.55T.
 
Computer Number: 12
2589. Rapid Dual-component UTE (RaD-UTE) imaging of bound and pore water in cortical bone
J. Athertya, A. Suprana, M. Carl, S. Xie, J. Lo, S. H. Shin, S. Jerban, E. Chang, Y. Ma, C. Chung, J. Du
Department of Radiology, UCSD, San Diego, United States
Impact: The RaD-UTE technique allows fast volumetric mapping of bound and pore water T1, T2*s, and fractions, and has great potential for accurate mapping of cortical porosity and organic matrix density under clinical acceptable scan time.
 
Computer Number: 13
2590. The optimized double echo steady-state (DESS) sequence for T2w fluid attenuation contrast at 7T
Q. Li, R. Chen, D. Wang, Y. Hsu, J. Qu, W. Liao
Siemens Healthineers Ltd., Shanghai, China
Impact: This study reported the first time the semi-FLAIR contrast at 7T without SAR limitation and B0 impact especially around sphenoid sinus using the low flip angle DESS sequence. 
 
Computer Number: 14
2591. Muscular Skeletal Perfusion Imaging using a UTE-Based DW-SSFP Sequence
K-J Jung
University of Illinois Urbana-Champaign, Urbana, United States
Impact: The new three-dimensional perfusion mapping sequence is very sensitive to perfusion of muscular skeletal tissue. This sequence can replace the spin-echo EPI diffusion sequence.  This will be useful in 7T MRI due to employing low flip angle RF pulses.
 
Computer Number: 15
2592. Open-source Multi-Spin Echo T2 Mapping Optimized for Knee Articular Cartilage
T. T. Fernandes, A. S. Gaspar, J. Schmidt, A. Alfaiate, P. Scheibe, J. M. Coelho, V. Mascarenhas, S. Geethanath, R. G. Nunes
Institute for Systems and Robotics - Instituto Superior Técnico – Universidade de Lisboa, Lisboa, Portugal
Impact: Multi-Spin Echo sequences for T2 mapping knee articular cartilage were made available as open-source vendor-agnostic tools to enable future quantitative MRI standardization studies. NIST phantom evaluation tests suggest improved precision with the proposed optimization. Pilot in vivo data demonstrates feasibility.
 
Computer Number: 16
2593. Highly Accelerated Pulmonary MRI Using RF Depolarization of 129Xe: The Sectoral Pulse Sequence
S. Perron, M. Fox, A. Ouriadov
The University of Western Ontario, London, Canada
Impact:

We present a significant acceleration method which uses RF depolarization of hyperpolarized gas in lungs to reduce 129Xe dose costs. This method results in clinically-viable lung images with up to 10-fold acceleration possible with a 3-fold reduction in 129Xe dose.

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