ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i
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Computer Number: 65
3721. Application
of passive intraoperative motor fMRI at 3T for the delineation
of the sensorimotor cortex
G. Hangel, J. Wais, M. Tomschik, F. Fischmeister, C. Dorfer,
G. Kasprian, K. Rössler
Medical University of Vienna, Vienna, Austria
Impact: 3T intraoperative passive motor fMRI under
general anaesthesia is feasible with the potential of
patient-individualised on-site brain-mapping of the
sensorimotor cortices for improved neuronavigation for
better functional outcomes and treatment monitoring.
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Computer Number: 66
3722. Brainstem
Functional Mapping During Motor Tasks with Ultra-High Field MRI
Y. Sun, D. Huang, L. Henderson, P. Austin, F. Calamante, Y.
Fu, J. Lv
University of Sydney, Sydney, Australia
Impact: Understanding brainstem motor function may
reveal early markers of Parkinson’s disease, bridging the
gap between molecular pathology and detectable brain
functional changes. This could advance early diagnosis and
deepen insights into PD-related neurodegeneration in motor
pathways.
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Computer Number: 67
3723. Functional
neural mechanisms and underlying structural changes are
associated with treatment efficacy in amblyopia
H. Singh, H. Gupta, R. Dhiman, S. S. Kumaran, R. Saxena
All India Institute of Medical Sciences, , New Delhi, India
Impact: By integrating imaging parameters and
identifying predictive factors for treatment response, it is
possible to develop more efficacious and individualized
treatment strategies for patients with amblyopia. The
functional-structural correlates observed in the study
suggest treatment response efficacy.
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Computer Number: 68
3724. BOLD
responses during stroop task correlates with glutamates and
gamma-aminobutyric acid at resting state
K. Ouchi, M. Fukunaga, T. Tsurugizawa
National Institute of Advanced Industrial Science and Technology (AIST), Ibaraki, Japan
Impact: This study reveals that the concentration of
Glu/GABA at resting state have a impact on brain activity
related to cognitive task, suggesting that these neural
metabolites could be useful as biomarkers for cognitive
function.
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Computer Number: 69
3725. Adaptive
approach for task fMRI group-level activation detection
X. Zhuang, Z. Yang, M. Lowe, D. Cordes
Cleveland Clinic Nevada, Las Vegas, United States
Impact: Improve the sensitivity and specificity of
task-fMRI group-level activation detection.
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Computer Number: 70
3726. Multimodal
characterization of inter-individual differences during auditory
statistical learning
J. Miehlbradt, D. Romascano, J. Wirsich, F. Grouiller, P.
Hüppi
University of Geneva, Geneva, Switzerland
Impact: We show that BOLD variability and EEG
entrainment are appropriate markers to assess
learning-specific brain activity patterns. In addition,
outcomes from these distinct imaging modalities present
similarities in spatial localization and explainability of
behavioral outcomes.
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Computer Number:
3727. WITHDRAWN |
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Computer Number: 71
3728. Comparing
Activation-Induced Changes in Cerebral Oxygen Metabolism
Measured by Calibrated fMRI and [15O]O2-PET
G. Deller, L. Liu, L. Narciso, J. Hicks, M. Langham, F.
Wehrli, K. St. Lawrence
Lawson Health Research Institute, London, Canada
Impact: This study is the first direct comparison of
c-fMRI to [15O]O2-PET and demonstrated the accuracy of the
MRI method.
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Computer Number: 72
3729. Near-silent
Looping Star fMRI during a passive listening task: preliminary
results
C. Ritter, A. Hüsser, A. Jakab, F. Wiesinger, B. Fernandez,
A. Solana, R. O´Gorman-Tuura, A. Hervais-Adelman
University of Geneva, Geneva, Switzerland
Impact: : LS may be a valid alternative for future
research utilizing auditory stimuli without the added
confound of background noise and the risk of adverse health
effects. The sequence might also be specifically suitable to
research sound averse populations.
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Computer Number: 73
3730. Assessing
diffusion changes in response to visual stimulation: A
multi-directional MPG approach in diffusion fMRI
I. KIDA
National Institute of Information and Communications Technology, Suita, Japan
Impact: dfMRI with multiple MPG directions enables more
localized brain activity mapping compared to BOLD-fMRI,
suggesting that water transport related to neuronal activity
may contribute to pseudo-diffusion effects in diffusion MRI
signals.
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Computer Number: 74
3731. Hemodynamic
activity in the putamen during motor-observation: initial
volunteers’ study with multi-echo EPI at 7 T
G. Baz, R. Schmidt
Weizmann institute of science, Rehovot, Israel
Impact: Functional MRI studies have shown mixed results
regarding whether the basal ganglia is active during motor
observation. Using a small cohort of subjects, we
demonstrate that motor observation does elicit a visible
hemodynamic response. Pronounced individual differences
invite further research.
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Computer Number: 75
3732. Brainstem
activation from sustained vowel phonation
H. Cheng, S. Brink, C. Smith, D. AAlto, S. Lulich
Indiana University, Bloomington, United States
Impact: Our results demonstrate the feasibility of
localizing brainstem nucleus with fast simultaneous
multi-slice EPI and sustained vowel phonation tasks.
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Computer Number: 76
3733. A
comparative analysis of single-echo and multi-echo EPI sequences
for task-fMRI
A. Giubergia, G. Ferrazzi, M. Castellaro, S. Mascheretti, V.
Lampis, F. Montano, A. Bertoldo, T. Ciceri, D. Peruzzo
IRCCS "Eugenio Medea", Bosisio Parini (LC), Italy
Impact: A comprehensive comparison of Multi-Echo fMRI
with an Optimized Single-Echo (OSE) acquisition (i.e. not
with data derived from ME itself) enables a direct
evaluation of two different acquisition approaches at their
best performances.
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Computer Number: 77
3734. Detection
of Neuronal Firings in Motor Cortex of Humans under a Task of
Finger-Tapping via Quantum-Sensing MRI
Y. Qian, K. Watson, X. Chen, Y-C Lin, S. Henin, N-M
Kumbella, J. Quimbo, Y. Ge, A. Masurkar, A. Liu, Y. Lui
New York University Grossman School of Medicine, New York, United States
Impact: This positive outcome will encourage researchers
to use the qsMRI in a wide range of studies on brain
functions and neurological disorders including normal aging
and Alzheimer’s disease.
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Computer Number: 78
3735. Consistency
mapping of a fMRI implementation of the Pyramids and Palm Trees
Semantic association task for presurgical language mapping
O. Parker Jones, P. Plaha, N. Voets
University of Oxford, Oxford, United Kingdom
Impact: The availability of comparable paradigms for use
in pre-surgical fMRI as well as during intra-operative awake
testing may help to improve evaluations of the clinical
relevance of fMRI predictions in patients undergoing awake
glioma surgery.
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Computer Number: 79
3736. Cognitive
Aging and Cerebellum: a task fMRI study of the older adults
Y. Lin, C-P Lin, L-H Chang, S-H Kuo
Columbia University, New York, United States
Impact: This study highlights the cerebellum's potential
role in compensating for cognitive decline in aging.
Identifying cerebellar activation patterns across tasks
could advance our understanding of brain aging mechanisms
and inform strategies to support cognitive resilience in the
older adults.
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