Digital Poster
Clinical Neuroscience: Stroke Pain Tumors
ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i
Digital Poster
Clinical Neuroscience: Stroke Pain Tumors
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Computer Number: 145
2715. Common
Neural Patterns of Substance Use Disorder: A Seed-based
Resting-State Functional Connectivity Meta-Analysis
F. Zhang
First Hospital of Shanxi Medical University, Tai Yuan, China
Impact: All substance use disorder individuals have the
same neural mechanism, which is the disruption of reward
circuits.
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Computer Number: 146
2716. Neural
networks and chemical messengers: Insights into tobacco
addiction
J. Sun, Q. Lv, J. Dang, M. Zhang, Q. Tao, Y. Kang, L. Ma, B.
Mei, W. Wang, S. Han, J. Cheng, Y. Zhang
First affiliated hospital of zhengzhou university, Zhengzhou, China
Impact: This study identifies specific brain network
alterations in tobacco addiction linked to neurotransmitter
systems, offering new targets for therapeutic interventions.
These findings may guide personalized treatments and
stimulate further research into the molecular mechanisms
underlying addiction.
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Computer Number: 147
2717. Abnormal
intrahemispheric and interhemispheric dynamic functional
connectivity density in alcohol use disorder
m. bohui, z. yong, c. jingliang
the First Affiliated Hospital of Zhengzhou University, zhengzhou, China
Impact: This
study identified the distribution of major central
connections at the hemispherical level of abnormal brain
networks that can be used as therapeutic targets in AUD
patients.
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Computer Number: 148
2718. Altered
Resting State Functional Connectivity Between High Order
Cognitive and Low Level Perceptual Networks in posttraumatic
stress disorder.
R. Zhong, Y. Gao, Y. Wang, Z. Zhou, W. Bao, L. Zhang, H. Li,
Q. Gong, X. Huang
Department of Radiology and Huaxi MR Research Center (HMRRC), Functional and Molecular lmaging Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, China
Impact: Our results of dysfunction within and between
different hierarchical network levels, with
hyperconnectivity in high-order-cognitive network and
between high-order-cognitive and low-level-perceptual
network in PTSD were disease-related, which is associated
with the key symptoms, potentially offering valuable targets
for therapeutic interventions.
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Computer Number: 149
2719. Relationship
between perivascular space markers and cognitive impairment in
subacute ischemic stroke
Y. Qin, X. Li, L. Wang, Y. Qian, Y. Qiao, W. Sheng, S. Wang
Department of Radiology, Xi'an Daxing Hospital, Xi'an, China
Impact: Our findings suggest that PVS burden and
DTI-ALPS index may contribute to the pathophysiology of
post-stroke cognitive impairment. This knowledge may
ultimately inform the development of targeted interventions
and therapeutic strategies aimed at preserving cognitive
function in this population.
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Computer Number: 150
2720. Pre-Stimulation
Resting-State Connectivity at Dentate Nucleus Stimulation
Contacts is Associated with Subsequent Motor Recovery
Post-Stroke
J. Chen, A. Nemani, X. Huang, S. Jones, M. Lowe, K. Baker,
A. Machado
Cleveland Clinic, Cleveland, United States
Impact: Our results show that pre-stimulation rsfMRI
connectivity of the brain at active contacts is associated
with subsequent motor recovery, supporting its use to
streamline the identification of optimal contacts to
activate for DN-DBS therapy to enhance post-stroke motor
recovery.
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Computer Number: 151
2721. Altered
regional homogeneity in patients with subacute ischemic stroke:
A longitudinal resting-state fMRI study
X. Li, Y. Qin, L. Wang, Y. Qian, W. Niu, Y. Qiao
Department of Radiology, Xi'an Daxing Hospital, Xi'an, China
Impact: The results of our study can objectively
identify local brain abnormalities in certain brain regions
of patients with ischemic stroke, which might be potential
targets for neural reorganization after stroke.
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Computer Number: 152
2722. Abnormal
cerebral blood flow and functional connectivity changes in
patients with MRI-negative focal epilepsy
D. Song, H. Zhang, Y. Liu, B. Chen, Z. Wang, J. Li, Y. Zhang
School of Clinical Medicine, Ningxia Medical University, Yinchuan, China
Impact: This study found that brain regions exhibiting
abnormal blood flow in epilepsy patients also undergo
functional alterations, providing valuable insights into the
pathophysiological mechanisms of focal epilepsy from the
perspective of neurovascular integration.
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Computer Number: 153
2723. Sensory
reweighting revealed by superior parietal lobule-based
functional connectivity in chronic ankle instability
R. Lu, X. Xue, S. Zheng, Z. Wang, Y. Chen, Z. Wang, Y.
Zhang, W. Tang, T. Hwang, Y-H Chu, Q. Li, Y. Sun, Y. Hua, H.
Wang
Huashan Hospital, Fudan University, Shanghai, China
Impact: The findings suggest that clinicians may focus
on somatosensory rehabilitation for CAI, which could
mitigate visual over-reliance in patients. This study
prompts further research into central mechanisms of sensory
reweighting, influencing treatment strategies and improving
outcomes for ankle sprain sufferers.
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Computer Number: 154
2724. Periaqueductal
Gray Functional Connectivity Abnormalities Associated with Acute
Post-Traumatic Headache
S. Nikolova, C. Chong, J. Li, W. Theresa, G. Dumkrieger, D.
Esterov, K. Ross, A. Starling, A. Thomas, M. Leonard, D.
Smith, T. Schwedt
Mayo Clinic, Phoenix, United States
Impact: Altered PAG FC could be predictive of PTH
outcome at 3 months. The high specificity of the model for
predicting PTH improvement implies that persistent PTH could
be detectable before it develops, allowing timely treatment
and pain management.
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Computer Number: 155
2725. Changes
in Gray Matter Volume of Thalamics Subregion in Patients with
Consciousness Impairment after Traumatic Brain Injury
X. Ma, J. Zhang, W. Huang, J. Yan, Z. Cheng, Y. Xiong
The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China
Impact: This study’s findings on thalamic atrophy in DOC
patients highlight potential targets for therapeutic
interventions, aiding clinicians in developing treatments to
improve consciousness. It opens new avenues for research
into thalamic functions and their role in consciousness
recovery.
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Computer Number: 156
2726. Longitudinal
Changes in Functional Connectivity during the First Year After
Moderate-to-Severe Traumatic Brain Injury
M. A. Yamin, J. J. Kim
CUNY School of Medicine, The City College of New York, New York, United States
Impact: This study highlights the evolving nature of
brain connectivity in TBI recovery, offering insights into
potential biomarkers of recovery and informing targeted
therapeutic strategies. These findings could aid in
developing personalized treatment plans for TBI patients.
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Computer Number: 157
2727. Brain
Structural and Functional Alterations in Chronic Multisite Pain:
A UK Biobank Study with a Focus on Sex Differences
V. Oliva, A. Banerjee, C. Law, D. You, L. Falasinnu, Y.
Wang, D. Pfyffer, M. Kaptan, G. Glover, S. Mackey, K. Weber
II
Italian National Institute of Health, Rome, Italy
Impact: The reproducibility crisis in neuroscience
impacts brain imaging studies with low sample sizes
especially. Results from large brain imaging datasets
obtained from the UK Biobank provide more generalizable
findings on the structural and functional changes in chronic
multisite pain patients.
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Computer Number: 158
2728. Resting-state
functional MRI study of brain functional activity changes in
patients with patent foramen ovale and migraine
Y. Li, Y. Liu, Q. Shang, J. Cao, X. Luo, J. Xin
Shandong Second Medical University, Weifang, China
Impact: This study explores the changes in brain
function in patients with PFO and migrainethrough brain
function imaging and identifies brain regions with abnormal
brain function activities. The ALFF value was correlated
with the severity of migraine.
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Computer Number: 159
2729. Distinct
salience network dynamics between the imagery and the experience
of migraine attacks
I. Esteves, A. Perdigão, A. R. Fouto, A. Ruiz-Tagle, G.
Caetano, J. Cabral, I. Pavão Martins, R. Gil-Gouveia, C.
Caballero-Gaudes, P. Figueiredo
ISR-Lisboa and Department of Bioengineering, Instituto Superior Técnico – Universidade de Lisboa, Lisbon, Portugal
Impact: We found salience network dynamics alterations
in migraine patients while performing an fMRI pain imagery
task. These are, however, not observed during the occurrence
of a migraine attack, which is likely more complex due to
other neuronal and vascular changes.
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Computer Number: 160
2730. Impact
of PFO Closure on CBF and GMV in Patients with Migraine
Associated with PFO: A Resting-State Multimodal MRI Study
Y. Zuo, W. Wang, Y. Dong
The Second Affiliated Hospital of Dalian Medical University, Dalian, China
Impact: Resting-state pcASL and VBM aid in exploring
neuroimaging mechanisms of headache relief in migraineurs
with PFO post-PFO closure.
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