ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

ISMRM & ISMRT 2025 Annual Meeting & Exhibition

Digital Poster

Stroke: Carotid Plaque & Ischemic Stroke

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Stroke: Carotid Plaque & Ischemic Stroke
Digital Poster
Neuro
Tuesday, 13 May 2025
Exhibition Hall
08:15 -  09:15
Session Number: D-142
No CME/CE Credit

 
Computer Number: 97
2357. Evaluation of the impact of carotid artery stenting on blood flow in carotid disease – a prospective follow-up MRI study
R. Kaur, P. Summers, W. Siu, X. Song
Simon Fraser University, Burnaby, Canada
Impact: Our findings suggest carotid artery stenting maintains or increases overall carotid blood flow, potentially benefiting functional recovery.  
 
Computer Number: 98
2358. Combination of Culprit Plaque Enhancement Ratio and Hypoperfusion Contributes to Outcomes of Patients with Middle Cerebral Artery Stenosis
S-S Wu, L. Wang, J-W Yu, Y. Wu, X-C Zhao, D-L Zhao
Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China
Impact: Our study included more factors related to the outcome of ischemic stroke and improved the accuracy in predicting the 90-day functional outcome of patients with ischemic stroke. This improvement can inform the planning of future clinical interventions.
 
Computer Number: 99
2359. Assessment of molecular and pH-weighted signal changes in chronic ischemic stroke using CEST MRI at 3T
J. Huang, M. Y. M. Chan, Y. Zhang, G. K. K. Lau, K. W. Y. Chan
The University of Hong Kong, Hong Kong, China
Impact: Chronic ischemic stroke brains exhibited decreased amide, rNOE, and MT signals, indicating reductions in proteins and lipids, along with an increased AACID signal suggesting a lower pH level. CEST MRI can monitor the prognosis of ischemic stroke in clinical settings.
 
Computer Number: 100
2360. The utility of 4D Flow MRI blood flow analysis in patients with cervical carotid artery stenosis
T. Ando, T. Sekine, K. Iwata, M. Nakaza, K. Suzuki, Y. Murai, S. Kumita
Nippon Medical School, Sendagi, Japan
Impact: In cases of carotid artery stenosis, TKE measured by 4D Flow MRI may serve as a parameter for characterizing the pathology of carotid artery stenosis and risk stratification.
 
Computer Number: 101
2361. Risk Factors for Co-existing Extracranial Carotid and Intracranial Artery High-Risk Atherosclerotic Plaques: A MR Imaging Study
X. Chen, D. Yang, X. Song, S. Chen, H. Qiao, C. Yuan, Z. Zheng, X. Zhao
Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China
Impact: To identify the risk factors for co-existing extracranial carotid and intracranial artery HRPs is valuable for precision management and prevention of future adverse events.
 
Computer Number: 102
2362. Anatomical location related hemodynamic variations are associated with MCA atherosclerosis: a preliminary 4D flow and 3D vessel wall MRI study
P. Jiang, L. Liu, H. Qiao, X. Xu, Y. Zheng, L. Lin, J. Chen, B. Sun, H. Wang, X. Zhao, Z. Chen, Y. Xue
Fujian Medical University Union Hospital, Fuzhou, China
Impact: Arterial segment, plaque number and plaque characteristics may have a significant interplay with the local hemodynamic environment, which could provide insight for atherosclerotic development.
 
Computer Number: 103
2363. Assessing the Predictive Impact of Corticocerebellar Pathway Integrity on Stroke Motor Outcomes
J. Liu, y. Shan, B-x Cui, S-z Yan, L-l Ye, B-y Xu, L. Cao, M. Zhang, J. Lu
Xuanwu Hospital, Capital Medical University, Beijing, China
Impact: Our study highlights the importance of corticocerebellar pathway integrity in predicting motor recovery after stroke. These insights can enhance early prognosis and guide personalized rehabilitation strategies for patients with middle cerebral artery infarction.
 
Computer Number: 104
2364. Evaluation of Middle Cerebral Artery Vessel Wall in Anterior Circulation Transient Ischemic Attack: A 5.0 T MRI and 3D High-Resolution Study
L. Yin, j. wang, Z. Li, d. yu, j. gan
Shandong Provincial Third Hospital, Jinan, China
Impact: This study demonstrates that 5.0 T MRI with high-resolution 3D-VWI can reliably identify high-risk structural changes in TIA patients, enhancing early stroke risk assessment and potentially guiding personalized intervention strategies for improved patient outcomes.
 
Computer Number: 105
2365. A Longitudinal Study of T2 Mapping and DTI to Quantitatively Evaluate Neuroprotective Effect of rTMS on Ischemic Rat Brain
Q. Zhang, A. Saeed, X. Tang, H. Shao, W. Liu, S. Huang, C. Liu, F. Guo, L. Peng, W. Zhu
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, wuhan, China
Impact: Parameters derived from T2 mapping and DTI can be used together as imaging biomarkers to assess the neuroprotective effect of rTMS on ischemic stroke. The longitudinal quantitative MRI evaluation provided new insights into the rTMS treatment for acute ischemic stroke.
   
Computer Number: 106
2366. Carotid Plaque Characteristics Predict Progression of White Matter Hyperintensities: A Prospective PET/MR Imaging Study
S. Zhang, M. Feng, S. Yan, J. Lu
Xuanwu Hospital Capital Medical University, Beijing, China
Impact: By identifying carotid plaque features that predict WMH progression, this study enables early identification of high-risk patients, guiding targeted interventions to prevent cerebral vessel disease progression and cognitive decline in those with carotid artery stenosis.
 
Computer Number: 107
2367. Quantitative assessment of carotid plaques vulnerability based on neovascularization and macrophage inflammation by hybrid PET/MR
Y. Zhang, J. Lu
Xuanwu Hospital Capital Medical University, Beijing, China
Impact: Reveal the vulnerable characteristics of neovascularization and inflammation within plaques, elucidate the correlation between the two and the pathophysiological mechanisms of plaque vulnerability, achieve early imaging warning, and effectively prevente the occurrence of ischemic stroke.
 
Computer Number: 108
2368. Post Treatment MRI Markers of Collateral Status Related to Adverse Events and Outcomes in Large Vessel Occlusion Acute Ischemic Stroke (LVO-AIS)
C. Greene, D. Lakhani, K. Chen, M. Kim, M. Hoseinyazdi, V. Yedavalli
Johns Hopkins University, Baltimore, United States
Impact: Preliminarily we demonstrate a relationship between FHVS and LVO-AIS complications and outcomes when accounting for patient and imaging factors. Post treatment MRI signs related to nuances in underlying tissue properties may thus help inform further patient assessment and treatment. 
 
Computer Number: 109
2369. Molecular basis of Gray Matter Volume Alterations in Ipsilesional and Contralesional Hemispheres after Subcortical Stroke
T. Jin, H. Gao, W. Hong, R. Xu, Z. Liu, Y. Wu, D. Wu, Y. Ma, Z. Zhao
Key Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China
Impact: Our findings demonstrate that contralesional increase and ipsilesional decrease in the GMV after stroke were linked to different molecular pathways and cellular types. These findings provide new insights into understanding brain damage and compensatory mechanisms after stroke.
 
Computer Number: 110
2370. Lesion detection in stroke patients based on intra-modality features on Diffusion MRI
S. Cao, Y. He, T. Wang, J. Qin, Y. Wu
Nanjing University of Science and Technology, Nanjing, China
Impact: This study emphasizes the advantages of diffusion sequences (ADC, TRACE)  in detecting brain tissue abnormalities while addressing the limitations of single-modal models. It also presents a novel method for developing multi-modal training models from a single modality.
 
Computer Number: 111
2371. High-fidelity Ultra-fast Diffusion Tensor Imaging in Stroke Patients Using Transfer Learning
Y. Jing, Z. Li, Y. Yu, J. Zhou, Z. Li, J. Zheng, H. Yang, M. Liu, W. Wu, Q. Tian, J. Lu
Tsinghua University, Beijing, China
Impact: Our work supports and promotes the feasibility of deep learning approach to benefit the clinical adoption of DTI for diagnosis and/or pre-surgical planning in scenarios where the scan time is extremely limited (e.g., for stroke patients).
 
Computer Number: 112
2372. The Application of New Models WMTI and MAPL in Assessing White Matter Microstructural Damage in Non-basal Ganglia Subcortical Ischemic Stroke
H. Wan, H. Su, Y. Li, W. Zhu
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Impact: Compared to traditional diffusion models DTI and DKI, the novel diffusion model MAPL exhibits higher sensitivity in describing changes in brain tissue microstructure. Additionally, changes observed during follow-up are positively correlated with NIHSS changes, making it a potential biomarker for estimating brain injury in ischemic stroke.
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