ISMRM25 - Blood Vessels I: Perfusion (non-ASL) & Other Techniques

ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

Blood Vessels I: Perfusion (non-ASL) & Other Techniques

Digital Poster

Neuro

Monday, 12 May 2025

Exhibition Hall

13:45 - 14:45

Session Number: D-160

No CME/CE Credit

		Computer Number: 113 1769. EXPLORING THE UNDERLYING MECHANISMS OF CHRONIC CEREBRAL BLOOD FLOW DEFICITS IN COVID-19 View Presentation Video N. van der Knaap, P. Voorter, B. van Bussel, I. van der Horst, J. Staals, R. van Oostenbrugge, W. Backes, D. Linden, J. Jansen, M. Ariës Maastricht University Medical Center, Maastricht, Netherlands Impact: Our findings suggest that chronically reduced CBF was not accompanied by altered microvascular architecture. Chronically reduced capillary perfusion was, however, preceded by hypercoagulation during the ICU period. The observed CBF deficits do not seem COVID-19-specific.
		Computer Number: 114 1770. The Correlation between Deep White Matter Hyperintensity and Hemodynamic Measurements of Perforating Arteries in Patients with CSVD View Presentation Video T. Chen, X. Pei, X. Zhang, Y. Zhao, Y. Li, Y. Yang, Y. Shi, Y. Wang, B. Sui Tiantan Neuroimaging Center of Excellence, China National Clinical Research Center for Neurological Diseases, Beijing, China Impact: Understanding the correlations between the hemodynamic measurements of the perforating arteries and the severity of DWMH may help to further understand the mechanism of cerebral white matter hypersensitivity.
		Computer Number: 115 1771. Regional Cerebral Perfusion after Automated Head-Up Cardiopulmonary Resuscitation using MRI View Presentation Video A. Metzger, X. Li, J. Moore, P. Pourzand, C. Lenglet, H. Farooq, D. Koski, B. Salverda, M. Suresh, H. Hai, K. Lurie, G. Metzger University of Minnesota, Minneapolis, United States Impact: The impact of active head up CPR on regional cerebral perfusion after return of spontaneous circulation will improve our understanding of the mechanisms responsible for the neurological survival benefits compared to conventional CPR.
		Computer Number: 116 1772. Comparison of brain structure and function in adult patients with unilateral versus bilateral asymptomatic moyamoya disease R. Hu, J. Lyu, Q. Duan, R. Li, C. Duan, S. Wang, X. Lou Department of Radiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China Impact: The decision regarding clinical intervention is complex for certain asymptomatic MMD cases. We investigated the structural and functional abnormalities in adults with unilateral and bilateral asymptomatic MMD, thereby establishing an imaging foundation for the informed selection of clinical interventions.
		Computer Number: 117 1773. Cerebrovascular reactivity dynamics in the postpartum period: a pilot study View Presentation Video J. Pinto, S. Suri, S. Sparks, G. Hayes, D. Bulte Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, United Kingdom Impact: This is the first MRI study investigating cerebrovascular reactivity changes in the postpartum period. Significant differences in reactivity timing were observed in specific regions of the brain known to be related to salience/reward networks and emotion processing.
		Computer Number: 118 1774. Deep Medullary Vein Density are associated with Paraventricular White Matter Hyperintensities and Brain Atrophy: An Automated Analysis of SWI View Presentation Video S. Maharjan, L. Alkhoury, X. Wang, L. Zhou, T. Butler, Y. Li, E. Tanzi, G. Chiang, M. de Leon, L. Glodzik Weill Cornell Medicine, New York, United States Impact: This study underscores the importance of venous health in CSVD, relating reduced DMVs density with PWMH pathology and brain volume, thus providing a potential additional biomarker for neurovascular pathology.
		Computer Number: 119 1775. Exploring the Utility of Quantitative MGRE in Distinguishing Migraine and Tension-Type Headache: A Pilot Study View Presentation Video Y. Yang The First Afﬁliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, hefei, China Impact: Our findings not only may serve as neuroimaging biomarkers to diagnose and predict in the two disorders, but also may ultimately be used in clinical performance by improving pain severity through depression regulation.
		Computer Number: 120 1776. Iron deposition in deep nuclei associated with cognitive function in cerebral small vessel disease: A quantitative susceptibility mapping study M. Feng, X. Liu, S. Zhang, B. Xu, J. Lu Department of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China Impact: It demonstrates the association between iron deposition in deep nuclei and cognitive dysfunction in CSVD, providing evidence for iron deposition in specific regions as a diagnostic marker and insight into the mechanisms of cognitive dysfunction, which guide future therapeutic strategies.
		Computer Number: 121 1777. Risk factors for the progression of white matter hyperintensity (WMH) in the patients with small vessel disease (CSVD)– A UK Biobank study View Presentation Video X. Han, Y. Hu, X. Gu, X. Yu, Y. Zhou Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong Universit, shanghai, China Impact: Our study highlights intricate relationships between clinical factors, imaging markers, and WMH progression.
		Computer Number: 122 1778. Large Blood Vessel Segmentation using Swin Transformers for Improved Quantitative DCE-MRI of Gliomas View Presentation Video A. Kesari, S. Maurya, M. Sheikh, R. Gupta, A. Singh Indian Institute of Technology Delhi, New Delhi, India Impact: The proposed transformer based LBV segmentation algorithm can aid radiologists in achieving more objective and accurate tumor assessment, potentially overcoming limitations associated with manual or semi-automatic segmentation techniques.
		Computer Number: 123 1779. Application of Dynamic Contrast-Enhanced MRI in Assessing Blood-Brain Barrier Permeability in SLE Patients View Presentation Video X. Zhao, Y. Sun, W. Meng, S. Wang, L. Zhou The Second Hospital of Hebei Medical University, Shijiazhuang City, China Impact: This study leverages DCE-MRI to assess BBB permeability across varying levels of SLE severity, exploring its association with neuropsychiatric impairment. These findings highlight DCE-MRI's potential as an imaging marker for early observation of BBB alterations in SLE patients.
		Computer Number: 124 1780. Diffusion along perivascular spaces index in patients after subarachnoid hemorrhage View Presentation Video P. Ulloa, J. Rudolf, A. Schmidt, J. Küchler, P. Schramm Universitätsklinikum Schleswig-Holstein, Lübeck, Germany Impact: We did not observe any interhemispheric differences in SAH patients and controls according the ALPS-index. Additionally, the ALPS index of SAH patients was lower than in controls, and there might be a negative correlation between the index and Hunt&Hess grading.
		Computer Number: 125 1781. Association Analysis of Systemic Inflammatory Response Index with Cerebral Small Vessel Disease and Imaging Biomarkers T. Zhuang, L. Han, Y. Cheng, Y. Zhang Ningbo Medical Center LiHuiLi Hospital, Ningbo, China Impact: These findings suggest that SIRI may serve as an inflammatory marker involved in CSVD development.
		Computer Number: 126 1782. Comparison of single-band versus multi-band phase contrast MRI for the estimation of pulse transit time as a measure of neurovascular stiffness View Presentation Video B. Keedwell, A. Hess, T. Okell, I. Dragonu, Y. Ji, M. Chiew, P. Jezzard University of Oxford, Oxford, United Kingdom Impact: Phase contrast MRI scans for the assessment of neurovascular stiffness can be accelerated by a factor of five through a simultaneous multi-slice acquisition without a significant difference in the reproducibility of pulse transit time measurements.
		Computer Number: 127 1783. Vascular pulsations in the rat brain visualized by EVEnt-Recurring ZTE (EVER-ZTE) View Presentation Video E. Paasonen, P. Stenroos, R. Salo, M. Kettunen, S. Michaeli, S. Mangia, J. Paasonen, O. Gröhn University of Eastern Finland, Kuopio, Finland Impact: EVER-ZTE enables the robust detection of brain vascular pulsations in preclinical settings, providing a unique opportunity to measure non-invasively critical physiological parameters linked to brain health at the same time with traditional fMRI measurement.
		Computer Number: 128 1784. BOLD MRI response to optogenetic activation of cerebral blood vessel cells in intact mouse brains View Presentation Video R. Yang, M. Rathnayaka, J. Wansapura, N. Li UT Southwestern Medical Center, Dallas, United States Impact: This work is the first to showcase the use of an ultrasensitive opsin to modulate hemodynamic signals transcranially without the need for invasive optical cannula implantation, marking a significant advancement in non-invasive genetically targeted hemodynamic modulation strategies.

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