Digital Poster
Neurodegeneration Is Not Only AD & PD II
ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i
Digital Poster
Neurodegeneration Is Not Only AD & PD II
 |
Computer Number: 129
3152. Cognitive
Impairment and Amygdala Subregion Volumes in Elderly with
Cerebral Small Vessel Disease: A Prospective Cohort Study
Z. Cheng, L. Yang, J. Li, Y. Chen, L. Pengcheng, W.
Yuanyuan, N. Wang, X. Zhang, C. Liang, M. Li, L. Guo
Binzhou Medical University, YAN TAI, China
Impact: These findings suggest that amygdala subregion
atrophy, particularly in the left cortical nucleus, may
serve as an early biomarker for cognitive impairment in
CSVD.
|
|
 |
Computer Number: 130
3153. Quantitative
MRI Correlates of Brain Non-heme Iron
Y. V. Sui, Z. Ben Youss, R. Flaherty, G. Schur, J. Chen, P.
Storey, M. Lazar
New York University Grossman School of Medicine, New York, United States
Impact: This
study examined MRI-based measures of non-heme brain iron,
providing valuable insights into their reliability as iron
markers across brain tissue types and their correspondence
with histology.
|
|
 |
Computer Number: 131
3154. Blunted
Hyperemia and Compromised Oxygen Delivery in Iron Deficiency
Anemia
C. González-Zacarías, E. Carpenter, S. Mejia, H. Salcudean,
B. Xu, S. Suriany, S. Verma, A. Joshi, P. Chiarelli, R.
Leahy, J. Wood
University of Southern California, Los Angeles, United States
Impact: These data suggest that physiological
compensation to compromised hemoglobin and erythrocyte
production in IDA is insufficient to maintain cerebral
oxygen delivery. Time-encoded pCASL may provide a biomarker
to indicate the necessity for medical intervention.
|
|
 |
Computer Number: 132
3155. Disease
Progression Patterns and Their Relationship with Cognitive
Function in Schizophrenia Through Subtype Analysis
A. Yuzawa, D. Yoshimaru, S. Shibukawa, M. Hirabayashi, E.
Hirakawa, H. Okano
The Jikei University School of Medicine, Tokyo, Japan
Impact: The identification of stage-specific brain
changes and their relationship to cognitive function
provides a framework for objective disease monitoring and
suggests potential targets for stage-specific therapeutic
interventions in schizophrenia.
|
|
 |
Computer Number: 133
3156. Amide
proton transfer magnetic resonance imaging to assess protein
metabolism in the brain of patients with T2DM and association
with cognition
H. Jiang, S. Yu, L. Yu, w. wang
Radiology department, The first affiliated hospital of Dalian medical university, Dalian City, China
Impact: This study demonstrates the value of APT imaging
technology applied to type 2 diabetes and provides a new
imaging method for assessing cognitive function in patients
with type 2 diabetes, which is beneficial for clinicians to
better monitor the condition.
|
|
 |
Computer Number: 134
3157. Altered
static and dynamic intrinsic brain activity patterns in type 2
diabetic mellitus patients
M. Li, H. Zhou, W. Liu
Zhanjiang First Hospital of Traditional Chinese Medicine, Zhanjiang, China
Impact: The study provided insights into both static and
dynamic brain function patterns in T2DM, highlighting
specific regions where functional impairments coincide with
cognitive decline. These findings underscored the importance
of both measures for early detection of T2DM-related brain
changes.
|
|
 |
Computer Number: 135
3158. Can
nigrosome 1 assessment via susceptibility map-weighted imaging
(SMwI) predict presynaptic DAT PET results in RBD patients?
B. Sohn, E. Y. Kim, E. Y. Joo
Samsung Medical Center, Seoul, Korea, Republic of
Impact: In RBD patients, nigrosome 1 evaluation using
SMwI showed moderate agreement with DAT PET. However, SMwI's
diagnostic sensitivity was lower than in Parkinson’s
disease, indicating it may not sufficiently replace DAT PET
in RBD diagnosis.
|
|
 |
Computer Number: 136
3159. The
relationship between cognitive impairment and changes in
cortical thickness and surface area of brain regions in patients
with preeclampsia
Y. Wang, M. li, X. Zhang, N. Wang, L. Yang, T. chen, L. Guo
Binzhou medical university, Yantai, China
Impact: The thickness of R-superior frontal is a signal
of cognitive impairment in patients, which provides
appropriate intervention timing and targets for clinical
practice. The thickness of L-pars opercularis mediates the
effects of pre-pregnancy BMI and MAP on cognitive
impairment.
|
|
 |
Computer Number: 137
3160. Study
on the Mechanism of Cognitive Impairment in NMOSD Patients
Mediated by the Reorganization of FC Related to Iron Metabolism
Abnormalities
X. Li, B. Liu, F. Li, L. Xu, X. Lin, J. Wang, Y. Liu, W.
Zhang, L. Lin, F. Ren, F. Gao
Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China
Impact: This study provides a new perspective on
elucidating the neural mechanisms of cognitive impairment in
NMOSD patients through the combined use of QSM and rs fMRI
techniques.
|
|
 |
Computer Number: 138
3161. Transient
Global Amnesia: Multi-timepoint 3T and 7T MRI Analysis of Acute
Hippocampal Lesions - A One-year Longitudinal Prospective Study
B. Wichtmann, Z. Bendella, M. Ferreira, M. Reuter, C.
Kindler, T. Rüber, A. Radbruch, G. Petzold, D. Paech, T.
Stöcker, F. Bode, N. von Danwitz
University Hospital Bonn, Bonn, Germany
Impact: Leveraging ultra-high field MRI, this study
provides evidence for clinicians and patients that acute
hippocampal lesions in TGA do not result in chronic
structural changes. The comprehensive multi-timepoint
imaging protocol establishes a methodological framework for
future investigations into TGA pathophysiology.
|
|
 |
Computer Number: 139
3162. Extracranial
Carotid Artery Disease is Associated with Decreased Ipsilateral
Cortical Surface Area in Regions Relevant to Cognitive Decline
H. Wiskoski, S. Zahra, J. Arias, Z. Khakwani, S. French, L.
Do, A. Pugazhendhi, R. Mushtaq, K. Johnson, M. Altbach, T.
Trouard, G. Alexander, C. Weinkauf
The University of Arizona, Tucson, United States
Impact: Findings highlight that aECAD impacts cortical
surface area rather than thickness, revealing a distinct
vascular pathway to dementia. This insight points to
potential targets for early intervention in high-risk
individuals and suggests further research into vascular
health’s role in neurodegeneration.
|
|
 |
Computer Number: 140
3163. Association
of Iron Level in the Nucleus Accumbens with Cognitive Impairment
in Preeclampsia
B. Chen, L. Yang, T. Chen, M. Li, L. Guo, N. Wang, X. Zhang,
Y. Wang, Z. Cheng, P. Liang, Y. Chen, X. Huo, F. Zhang
Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, Jinan, China, China
Impact: This study introduces a novel indicator that
utilizes QSM techniques for early prediction of preeclampsia
and associated cognitive impairment, potentially
improving diagnostic accuracy and intervention strategies.
|
|
 |
Computer Number: 141
3164. Application
of NODDI in Characterizing Brain Microstructural Changes in
Classical Trigeminal Neuralgia
Y. XIONG, J. Wang, W. Cui, W. Zhu
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Impact: This study highlights that NODDI technique
contributes additional information about the neurite density
and orientation dispersions in brain, directly relating to
neuronal morphology. It offers greater specificity than DTI
and improves the characterization of microstructural
alterations in TN.
|
|
 |
Computer Number: 142
3165. Association
Between Type 2 Diabetes Mellitus and Cognitive Impairment
Mediated by Imaging Markers of the Glymphatic System
P. Pan, J. Gao, K. Ai, X. Lei, X. Zhang
Shaanxi Provincial People's Hospital, Xi'an, China
Impact: The glymphatic markers is a promising imaging
marker for cognitive impairment and may provide clinicians
with important information for planning treatment strategies
and assessing prognosis in T2DM patients.
|
|
 |
Computer Number: 143
3166. Associations
of Glymphatic System Function with White Matter Alterations and
Cognitive Impairment in Type 2 Diabetes
Y. XIONG, Y. Li, J. Wang, W. Zhu
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Impact: This study highlights that the DTI-ALPS
technique and PSMD estimates can provide valuable insights
into physiological mechanisms of T2DM, especially those with
cognitive impairment, and offers greater specificity in
detecting glymphatic system function and global white matter
changes.
|
|
 |
Computer Number: 144
3167. Association
of Choroid Plexus Volume and Preeclampsia：A Research Based on
Magnetic Resonance Imaging
B. Chen, L. Yang, T. Chen, M. Li, L. Guo, N. Wang, X. Zhang,
Y. Wang, Z. Cheng, P. Liang, Y. Chen, X. Huo, F. Zhang
Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, Jinan, China, China
Impact:
This study introduces a novel indicator that utilizes choroid plexus volume and the QSM technique for early prediction of preeclampsia, potentially improving diagnostic accuracy and intervention strategies. |
Back to Meeting Home
Back to the Program-at-a-Glance
The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
View
Presentation Video