ISMRM25 - Advanced Lung MR Imaging

ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

ISMRM & ISMRT 2025 Annual Meeting & Exhibition

Digital Poster

Advanced Lung MR Imaging

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Advanced Lung MR Imaging

Digital Poster

Body

Tuesday, 13 May 2025

Exhibition Hall

08:15 - 09:15

Session Number: D-55

No CME/CE Credit

		Computer Number: 1 2261. Morphological performance of free breathing stack-of-spirals ultrashort echo time MRI for malignant lung nodules Q. Fu, J-w Wu, X. Sun, X-n Meng, A-d Xiao Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Impact: Spiral-UTE provides a potential alternative to CT for showing malignant lung nodules, and with significantly superior visualization of morphological features compared to routine enhanced-VIBE. Enhanced spiral-UTE offered superior SNR and CNR for detecting subtle details of malignant nodules than unenhanced spiral-UTE.
		Computer Number: 2 2262. A Method to Improve the Reliability of Pulmonary Perfusion-weighted Maps Obtained Using 3D Ultrashort Echo-time MRI View Presentation Video H. Kim, S. Lee, J. Park, Y. J. Oh, J. Kim, J. Choe, H. Y. Lee, J-Y Park Sungkyunkwan University, Suwon, Korea, Republic of Impact: Improves the reliability of the 3D non-contrast enhanced perfusion-weighted map by effectively removing unwanted signals due to registration errors combined with low SNR and undersampling during image processing.
		Computer Number: 3 2263. T1 Mapping in the Lungs using a Variable Flip Angle Approach with UTE-MRI View Presentation Video S. Khodaei, A. Kizhakke Puliyakote, C. Wharff, M. McIntosh, R. Meyer, O. Aboderin, K. Staab, A. Hahn, S. Fain The University of Iowa, Iowa City, United States Impact: The free-breathing VFA-UTE technique provides a simple and time-efficient approach to generate high-resolution 3D parametric mapping of lung parenchyma during free breathing that is sensitive to changes in physiological conditions.
		Computer Number: 4 2264. 3D Ultrashort Echo Time (UTE) and 2D Dynamic MRI for Evaluating Ventilation and Chest Wall Motion in Pediatric Pectus Malformation Patients View Presentation Video B. Mei, F. Tan, S. Kim, P. Larson University of California, San Francisco, San Francisco, United States Impact: UTE and dynamic MRI-based ventilation analysis and chest motion tracking greatly boost the structural and functional understanding of pectus deformities and pave the road to novel discoveries about the etiology of pectus deformities and better treatment decisions under clinical settings.
		Computer Number: 5 2265. Magnetization Transfer Imaging of the Lung at 0.55T View Presentation Video A. Braun, G. Bauman, O. Bieri University of Basel, Allschwil, Switzerland Impact: This work shows that high-resolution in-vivo magnetization transfer imaging of the lung is feasible and reproducible at 0.55T in free-breathing and within clinically relevant scan times, offering excellent prospects to detect lung tissue abnormalities such as fibrosis.
		Computer Number: 6 2266. Quantification of Gas Trapping in Cystic Fibrosis using Expiratory Breath-Hold Lung ¹H-MRI View Presentation Video A. Simmons, L. Smith, Z. Somerville, H. Faulke, B. Tahir, D. Hughes, N. West, A. Biancardi, N. Stewart, J. Wild POLARIS, Division of Clinical Medicine, Faculty of Health, The University of Sheffield, Sheffield, United Kingdom Impact: We developed a workflow to quantify gas trapping in CF using a standard, easily implementable 1H-MRI sequence. Our proposed metric sensitively quantifies gas trapping in individuals with normal spirometry, suggesting its potential for early disease assessment.
		Computer Number: 7 2267. Respiration Monitoring with Remote Pneumatic Dose Administration for 129Xe MRI View Presentation Video D. Clements, S. Leewiwatwong, A. Costelle, A. McHorse, S. Lee, C. Blanton, J. Korzekwinski, A. Sents, J. Shaffer, S. Harris, D. Mummy, B. Driehuys Duke University Medical Center, Durham, United States Impact: Monitoring subject respiration prior to hyperpolarized ¹²⁹Xe administration reveals altered respiration patterns. This work will inform new approaches for consistent subject coaching and dose delivery to improve repeatability of lung inflation during imaging.
		Computer Number: 8 2268. Visualization of Vasoactive Treatment by Hyperpolarized Xenon-129 MRSI and Cardiogenic Oscillations View Presentation Video M. Andersen, M. Kristensen, E. Hansen, R. Schulte, M. Redda, U. Kjærgaard, M. Væggemose, C. Laustsen Aarhus University, Aarhus N, Denmark Impact: Hyperpolarized 129Xe MRSI enables non-invasive monitoring of pulmonary hypertension, facilitating early diagnosis and precise hemodynamic assessment. This approach supports optimized treatment, reduces hospitalizations, and enhances quality of life and survival in chronically ill patients.
		Computer Number: 9 2269. Explainable AI-based classification of asthma and COPD from 129Xe-MRI with regional interpretability View Presentation Video J. Astley, H. Marshall, L. Smith, A. Biancardi, R. Hughes, B. Tahir, J. Wild University of Sheffield, Sheffield, United Kingdom Impact: Novel use of xenon-129 (¹²⁹Xe)-MRI to classify patients with asthma and/or COPD. Explainable AI techniques provide insights into regional patterns of ventilation associated with classifications; large-scale regional patterns that occur in ¹²⁹Xe-MRI show qualitative differences in asthma and/or COPD phenotypes.
		Computer Number: 10 2270. Comparison of Inert Fluorinated Gas and Hyperpolarized 129Xe Lung MRI Image Quality in Pediatric Participants View Presentation Video B. Zanette, F. Alam, F. Ratjen, G. Santyr The Hospital for Sick Children, Toronto, Canada Impact: PFP-MRI may offer comparable ventilation information to Xe-MRI in children with reduced costs and infrastructure complexity, despite lower SNR and resolution.
		Computer Number: 11 2271. Use of Principal Component Analysis to Study Features Within Functional 1H Lung MRI at 3 T View Presentation Video Z. Peggs, S. Francis, P. Gowland University of Nottingham, Nottingham, United Kingdom Impact: PCA may provide a method to gain additional functional insight from, and enhance the SNR of, ¹H ventilation and perfusion maps.
		Computer Number: 12 2272. Half-Radial Balanced Steady-State Free Precession for Functional Lung Imaging with Matrix Pencil Decomposition at 3T View Presentation Video A. Leuthard, G. Bauman, O. Bieri University of Basel, Allschwil, Switzerland Impact: This work demonstrates that functional lung matrix pencil decomposition MRI using half-radial bSSFP is feasible at 3T. The adapted acquisition scheme helps to supress off-resonance artifacts and can be used as an alternative to the contemporary Cartesian k-space sampling approach.
		Computer Number: 13 2273. Conjugate Gradient and DL Reconstructions for UTE-MRI: Reducing Scan Time without Image Quality and Nodule Detection Capability Degradations View Presentation Video M. Endo, Y. Ohno, K. Yamamoto, Y. Sano, M. Ikedo, M. Ozaki, M. Yui, H. Nagata, T. Ueda, M. Nomura, T. Yoshikawa, D. Takenaka, Y. Ozawa Shizuoka Cancer Center, Sunto-gun, Japan Impact: When compared with conventional grid reconstruction, conjugate gradient reconstruction and deep learning reconstruction are useful for reducing acquisition time without degradations of image quality and nodule detection on pulmonary MRI with ultra-short TE.
		Computer Number: 14 2274. Comparison of MRI and CT in Detecting Pulmonary Lesions: Consistency and Prospects for Application View Presentation Video L. Hairong, J. Rongrong, Z. Lang, S. Linqiang, H. Guangxu, Q. Kaili, G. Yanjun The Affliated Hospital of Northwest University·Xi 'an No.3 Hospital, Xi'an, China Impact: This study provides guidance on MRI scanning strategies for pulmonary lesions, recommending the respiratory-gated 3D ZTE sequence as the primary choice for subsolid lesions.
		Computer Number: 15 2275. Exploring Brain Differences in Lung Cancer Patients with Varying Lymph Node Statuses: A Preliminary Study Based on DTI-ALPS X. Liu, N. Meng, J. Pan, Z. Wang, Y. Yang, J. Yuan, M. Wang Zhengzhou University People's Hospital, Zhengzhou, China Impact: This study offers a novel perspective on how lung cancer lymph node status impacts the central nervous system, revealing the interaction between tumor behavior and the brain, and suggesting that lymph node metastasis may affect the brain microenvironment.
		Computer Number: 16 2276. Impact of Segmentation Masks on Deformable Image Registration in Post-Processing of Functional Lung MRI View Presentation Video J. Heidenreich, S. Westphale, J-P Grunz, S. Veldhoen, H. Koestler, T. Wech University Madison Wisconsin, Madison, United States Impact: The robustness of image registration is crucial for calculating ventilation in functional lung MRI. Selecting optimal weighting masks to support registration can significantly enhance precision, impacting the accuracy of functional ventilation post-processing.

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