ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i
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Computer Number: 81
3264. Green-EPT
L. Zilberti, A. Arduino, U. Zanovello, J. Martinez Martinez,
K. Moulin, A. Troia, O. Bottauscio
Istituto Nazionale di Ricerca Metrologica, Torino, Italy
Impact: Green-EPT is a new approach for MR-based
Electric Properties Tomography. Validation tests, including
in vivo studies, demonstrate that the approach performs well
and is worth pursuing further.
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Computer Number: 82
3265. Susceptibility
source separation unveils iron and myelin trajectories in
healthy brain development and aging
T. Oliveira Assuncao, N. Naji, P. Seres, C. Beaulieu, A.
Wilman
University of Alberta, Edmonton, Canada
Impact: Paramagnetic
and diamagnetic maps unveiled independent iron and myelin
trajectories in development and aging, removing confounds
found in total susceptibility.
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Computer Number: 83
3266. Investigating
the association between conductivity and brain development over
the neonatal period
A. Boutillon, R. Kurtzbard, O. Gale-Grant, A. Price, J.
Hand, D. Batalle, M. Deprez, S. Malik
King's College London, London, United Kingdom
Impact: This preliminary study showed a consistent and
significant linear decrease in brain conductivity (-0.012 to
-0.014 S/m/week) during the neonatal period. This is likely
driven by changes in water content, but future work will
explore a biophysical explanation.
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Computer Number: 84
3267. Improving
Data Consistency and Generalizability in Deep Learning-Based QSM
Reconstruction
Y. Zhang, Y. Li, R. Liu, Z. Ke, W. Jin, Y. Zhao, Y. Li, Z-P
Liang
University of Illinois at Urbana-Champaign, Urbana, United States
Impact: With improved data consistency and
generalizability, the proposed method could significantly
enhance the reliability of AI-powered QSM reconstruction,
making it a practically useful tool to support a wide range
of QSM studies in scientific and clinical applications.
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Computer Number: 85
3268. Exploring
vessel artifacts in χ-separation
T. Kim, S. Ji, J. Lee
Seoul National University, Seoul, Korea, Republic of
Impact: This study identifies sources of vessel
artifacts in χ-separation,
improving our understanding of χ-separation
maps and also suggesting the need for caution when
analyzing χ-separation.
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Computer Number: 86
3269. On-scanner
Reconstruction for Susceptibility Source Separation
N. Naji, J. Grenier, J. Snyder, K. Chow, L. Cui, G. Moran,
A. Wilman
University of Alberta, Edmonton, Canada
Impact: The implemented reconstruction tool enables
producing para- and diamagnetic maps directly on the
manufacturer’s scanners without the need for offline
processing.
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Computer Number: 87
3270. Quantitative
Susceptibility Mapping at 7T Using Bilateral Orthogonality
Generative Acquisitions Method
Ç. Boğa, Y. Huang, J. Liu, A. Henning
UT Southwestern Medical Center , Dallas, United States
Impact: Effects of the transmit field inhomogeneity on
susceptibility mapping can be eliminated with BOGA method,
particularly at lower brain regions. Which can further
increase the utilization of susceptibility mapping in lower
brain regions.
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Computer Number: 88
3271. Evaluating
the Static Dephasing Regime Assumption for Gradient Echo Signal
in Brain Cells
A. Alpman, C. Liu
University of California, Berkeley, Berkeley, United States
Impact: The static dephasing assumption, commonly used
to model magnetic susceptibility effect within a voxel, may
fail in brain microstructure, particularly in regions with
restricted/hindered diffusion and high axonal volume
fraction, highlighting the necessity of incorporating
diffusion effects.
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Computer Number: 89
3272. Conductivity
reconstructions with polynomial fitting using subvoxel FOV
shifts
T. Meerbothe, C. van den Berg, S. Mandija
University Medical Center Utrecht, Utrecht, Netherlands
Impact: With multiple low-resolution Cartesian
acquisitions using subvoxel-shifts, reconstructed
conductivity is more robust to noise, in comparison to
conventional methods for similar scan times. The higher
quality reconstructions can be important for clinical
application of EPT in the future.
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Computer Number: 90
3273. A
Deep Learning based Harmonic Field Extension in SMWI with
Reduced Spatial Coverage
S. Jung, S-M Gho, S. Jeon, D-H Kim
Yonsei University, Seoul, Korea, Republic of
Impact: This study offers a practical approach to
enhance SMWI contrast in limited FOV scans, enabling faster,
more effective imaging for Parkinson’s patients. The method
holds potential for clinical application with reduced scan
time and robust contrast maintenance.
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Computer Number: 91
3274. The
Application of Magnetic Susceptibility Separation for Measuring
Cerebral Oxygenation in Preterm Neonates
T. Carmichael, A. Rauscher, R. Grunau, A. Weber
The University of British Columbia, Vancouver, Canada
Impact: Magnetic susceptibility separation, an MRI
post-processing technique, shows promise as a non-invasive
method of measuring regional cerebral oxygenation in
neonates, and may serve as tool for clinicians and
researchers alike.
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Computer Number: 92
3275. Phase-based
Electrical Conductivity as a Potential Imaging Marker of
Treatment Effectiveness in Lumbar Intervertebral Disc Herniation
K. Tha, M. Kitagawa, M. Saito, P. Song, K. Yamada, H. Sudo,
U. Katscher
Hokkaido University Faculty of Medicine, Sapporo, Japan
Impact: This is the first study which evaluated
treatment effectiveness of surgery (standard discectomy and
UPAL gel implantation) in lumbar IVD degeneration using a
recently developed noninvasive quantitative MRI index, i.e.,
σ of IVD.
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Computer Number: 93
3276. Unraveling
the Hidden Link: Electrical Conductivity-Apparent Diffusion
Coefficient Correlation Patterns in Thoracic Lesions
J. Wang, U. Katscher, E. Kikuchi, M. Kitagawa, Y. Kikuchi,
Y. Yoshino, P. Song, K. K. Tha
Laboratory for Biomarker Imaging Science, Hokkaido University Graduate School of Medical Science and Engineering, Sapporo, Japan
Impact:
This study informs the positive relationship between σ and ADC in thoracic lesions, highlights the factors that influence this relationship, and the importance of integrating σ and ADC in evaluating lesion microarchitecture.
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Computer Number: 94
3277. Physics-Informed
Complex-Valued Network for Electrical Properties Tomography in
7T MRI Using Multi-Channel Receive Arrays
M. Zheng, X. Zhang
College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, China
Impact: This approach utilizes
$$$\overrightarrow{B_{1}^{-}}$$$ magnitude and relative
phase data from regular receive array to reconstruct EPs. It
requires no additional hardware or complex software,
offering potential for clinical MREPT applications.
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Computer Number: 95
3278. Age-Related
Patterns of Deep Grey Matter Magnetic Susceptibility in
Tanzanian Children with Sickle Cell Anaemia
M. Lee, M. Jakob, M. Elgwely, F. Kirkham, K. Shmueli
University College London, London, United Kingdom
Impact:
Different patterns of age-related susceptibility accumulation observed in some deep grey-matter regions in children with SCA compared to controls motivate efforts to fully characterize changes to susceptibility and other tissue properties across the lifespan, using QSM and other quantitative techniques. |
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Computer Number: 96
3279. Quantitative
and Qualitative Impact of Magnetic Microstructure on
Conventional and Deep Learning-based Quantitative Susceptibility
Mapping
T. Jochmann, F. Salman, M. Dwyer, N. Bergsland, R. Zivadinov,
J. Haueisen, F. Schweser
Technische Universität Ilmenau, Ilmenau, Germany
Impact:
This work demonstrates that incorporating microstructure-induced frequency shifts into QSM significantly enhances susceptibility mapping accuracy, particularly in white matter. These findings enable improved study of pathologies with microstructural alterations, providing clinicians and researchers with more reliable maps for disease assessment. |
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