ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

ISMRM & ISMRT 2025 Annual Meeting & Exhibition

Oral

Quantitative Imaging

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Quantitative Imaging
Oral
Acquisition & Reconstruction
Wednesday, 14 May 2025
323AB
08:15 -  10:15
Moderators: Kwok-Shing Chan & Mikko Nissi
Session Number: O-02
CME Credit

08:15 0810. Liver Proton Density Fat Fraction (PDFF) at 0.55T Using Locally Low-Rank Deep Learning (LLR-DL) Reconstruction
M. Helo, M. Nickel, S. Kannengiesser, T. Kuestner
Medical Image and Data Analysis (MIDAS.lab), Department of Diagnostic and Interventional Radiology, University of Tuebingen, Tuebingen, Germany
Impact: Multi-echo Dixon acquisitions with short echo times combined with iterative DL-based reconstruction using locally low-rank regularization yields high SNR images. This approach enables precise PDFF quantification and provides high-SNR R2* maps at 0.55T.
08:27 0811. Highly Accelerated T1 and T2 Mapping in Water-Unsuppressed MRSI Using Generalized Series Modeling and Deep Learning
Y. Li, R. Guo, Y. Zhao, W. Jin, S. Luo, K. Lu, L. Cao, Y. Li, V. Kindratenko, M. Anastasio, B. Sutton, Z-P Liang
University of Illinois at Urbana-Champaign, Urbana, United States
Impact: The proposed method provides a powerful multimodal imaging capability that provides tissue structural and biochemical biomarkers at the same time. This new imaging technology may enable better tissue characterization desired for various research and clinical applications.
08:39 0812. MIMOSA: Multi-parametric Imaging using Multiple-echoes with Optimized Simultaneous Acquisition for highly-efficient quantitative MRI
Y. Chen, Y. Jun, A. Heydari, X. Yong, H. Liu, H. Ye, B. Gagoski, B. Bilgic, S. Fujita
Zhejiang University, Hangzhou, China
Impact: MIMOSA enables whole-brain T1, T2, T2*, PD, QSM, para- and dia-magnetic susceptibility mapping at 1mm isotropic resolution in 3min at 3T and 750μm in 13min at 7T, achieving susceptibility source separation in a single scan for comprehensive tissue characterization.
08:51 0813. Towards Single-Shot Whole-Heart T1 Mapping Within Four Seconds
D. Mackner, M. Blumenthal, N. Scholand, M. Huemer, M. Schilling, V. Telezki, X. Wang, M. Uecker
Graz University of Technology, Graz, Austria
Impact: High resolution multi-slice $$$T_1$$$ quantification covering the whole-heart can be achieved within a short breath-hold of four seconds, which improves patient comfort, reduces motion artifacts, and improves the clinical feasibility of whole-heart $$$T_1$$$ mapping.
09:03 0814. Diffusion Tensor Imaging of Short T2 Tissues Using Quantitative Ultrashort Echo Time Double Echo Steady State (qUTE-DESS)
J. Park, S. Sedaghat, E. Fu, Y. Jung, L. Nardo, A. Chaudhari, H. Bang, H. Jang
University of California, Davis, Sacramento, United States
Impact: qUTE-DESS-based DTI may provide accurate information on collagen (via FA) and proteoglycan content (via MD) in both short and long T2 tissues throughout the joint, enabling a comprehensive assessment of musculoskeletal disorders such as osteoarthritis.
09:15 0815. Efficient mesoscale multiparametric quantitative MRI using 3D-QALAS at 7T with self-supervised learning
Y. Jun, S. Fujita, Y. Chen, A. Mareyam, C. Jaimes, M. Gee, B. Gagoski, B. Bilgic
Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, United States
Impact: We demonstrate high-fidelity mesoscale (500µm isotropic resolution) multiparametric qMRI with 3D-QALAS at 7T using self-supervised image reconstruction and parameter estimation.
09:27 0816. Saturation Recovery Chemical Shift-Encoded T1 Mapping in the Liver
G. Fullerton, D. Tamada, Y. Muslu, D. Hernando, S. Reeder
University of Wisconsin-Madison, Madison, United States
Impact: The proposed optimized acquisition strategy improves the noise performance of 2D confounder-corrected liver T1 mapping, enabling robust liver coverage (9 slices) in a 20-second breath-hold. This improves the clinical viability of confounder-corrected T1 mapping for assessing liver disease.
09:39 0817. Efficient 3D whole-heart joint T1/T1ρ-adiabatic/T2 mapping and water-fat imaging at 0.55T
M. Crabb, D. Si, S. Littlewood, K. Kunze, C. Prieto, R. Botnar
King's College London, London, United Kingdom
Impact: 3D whole-heart T1, T1ρ-adiabatic and T2 maps and co-registered water-fat volumes with isotropic resolution for comprehensive myocardial tissue characterization can be obtained in a single scan of ~10 min at 0.55T.
09:51 0818. Comparison of Myelin Fraction Maps Acquired with mcUTE, T2 Relaxation and Magnetization Transfer
N. Yin, A. Rau, M. Reisert, K. Tadjalli Mehr, S. Liu, M. Helmstaedter, M. Schwabenland, U. Emir, M. Bock, A. Caglar Özen
University Medical Center Freiburg, University of Freiburg, Freiburg, Germany
Impact: mcUTE reliably provides whole-brain myelin fraction maps and high-resolution water-excited anatomical image data in less than 15min at a clinical MRI system. Ex vivo results showed that myelin imaging using mcUTE is highly consistent with electron microscopy.
10:03 0819. Fat quantification using a phase error-corrected cartesian acquisition with spiral profile ordering (CASPR)
P. Braun, J. Stelter, S. Ruschke, J. Peeters, H. Eggers, K. Weiss, D. Junker, D. Karampinos
School of Medicine and Health, Technical University of Munich, Munich, Germany
Impact: Prior studies have established the CASPR trajectory as an efficient and easily customizable trajectory with self-gating motion capabilities. This work is the first to use the CASPR trajectory for fat quantification, while simultaneously addressing phase error effects.
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