ISMRM25 - Open-Source Sequences & High-Dimensional Imaging

ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

Open-Source Sequences & High-Dimensional Imaging

Oral

Acquisition & Reconstruction

Thursday, 15 May 2025

316B

13:15 - 15:15

Moderators: Andreia Gaspar & Ludovica Romanin

Session Number: O-07

No CME/CE Credit

13:15		1273. Open-Source Implementation for X-Nuclear and Multi-Site Sequences within the Pulseq Framework View Presentation Video X. Liu, D. Cui, P. Larson, D. Mayer, J-F Nielsen, R. Schulte, C. Mu, L. Carvajal, D. Xu, J. Gordon, D. Vigneron, A. Korzowski, R. Flavell, Z. Wang University of California San Francisco, San Francisco, United States Impact: X-nuclear sequence developers can now more easily transfer their sequences across vendors and software for multi-site studies.
13:15		1274. Open EPTI: pluggable, distortion-free continuous readout developed on vendor-neutral Pulseq for versatile multi-contrast MR imaging View Presentation Video J. Wu, T. Reese, S. Fujita, B. Bilgic, L. Wald, Z. Dong, F. Wang Massachusetts General Hospital, Charlestown, United States Impact: We developed EPTI into vendor-neutral sequence/reconstruction frameworks, providing a pluggable, distortion-free readout for multi-contrast MR imaging. As proof-of-concept, we demonstrated Pulseq-EPTI readout in three contrast acquisitions tailored to three different applications, including quantitative MRI, fMRI, and CEST imaging.
13:15		1275. Pulserver: an open-source Pulseq-based client-server framework for vendor agnostic, interactive MR sequence design View Presentation Video M. Cencini, K. Wang, S. Huang, R. Schulte, T. Sprenger, D. Noll, M. Tosetti, J-F Nielsen INFN, Pisa Division, Pisa, Italy Impact: Our framework bridges the low-access barrier of vendor-agnostic design frameworks like Pulseq with the interactive customizability of native vendor-provided sequences, enabling faster prototyping and deployment of novel techniques in clinical workflows.
13:15		1276. A Hybrid Multi-Echo Radial Look-Locker (hME-rLL) multi-slice framework for efficient liver coverage in joint T1-water, PDFF, and R2* estimation View Presentation Video E. Ahanonu, U. Goerke, B. Toner, K. Johnson, R. Akhbari, G. Block, D. Martin, V. Deshpande, X. Zhong, H. Wu, A. Bilgin, M. Altbach University of Arizona, Tucson, United States Impact: Joint estimation of T1-water, PDFF, and R2* would allow for more efficient evaluation of liver condition for diagnosis and monitor of patients with steatotic liver disease.
13:15		1277. Quantification of the Vocal Fold Oscillations from 3D-isotropic Sub-millimeter Sub-millisecond MRI View Presentation Video P. Jordan, J. Fischer, F. Stritt, M. Köberlein, L. Traser, B. Richter, M. Bock University Medical Center Freiburg, Freiburg, Germany Impact: VF MRI provides valuable contributions to the measurement of the VF dynamics in vivo under diverse physiological conditions. After adaptation, the method might provide insights into the dynamics of other oscillatory structures such as the heart valves.
13:15		1278. DREAMER: Rapid, high-resolution, and simultaneous multiple-contrast magnetic resonance imaging of solid and soft tissues View Presentation Video B-T Vu, N. Kamona, F. Wehrli, E. Baccaglini, C. Rajapakse University of Pennsylvania, Philadelphia, United States Impact: DREAMER jointly images solid and soft tissues. The sequence may enable consolidation of CT and MRI demand at imaging centers, thereby decreasing patient examination and wait times, reducing exposure to ionizing radiation, and simplifying the clinical workflow.
13:15		1279. Comparison of mtrk, Pulseq, and vendor sequences using simulated, phantom, and in-vivo acquisitions View Presentation Video A. Artiges, A. Singh Saimbhi, C. Castillo-Passi, E. Montin, I. Giannakopoulos, R. Lattanzi, K. Block New York University Grossman School of Medicine, New York, United States Impact: mtrk can improve the reproducibility, accessibility, and dissemination of pulse sequences through an intuitive development environment. Its human-readable descriptive language, its compatibility with Pulseq, and its agreement with vendor sequences make mtrk a powerful open-source tool for MRI pulse-sequence development.
13:15		1280. Efficient 5D Motion Resolved Imaging: Assessing Spatial Resolutions for Faster Acquisition Without Compromising LV Ejection Fraction Accuracy View Presentation Video J. Yerly, A. Ogier, C. Roy, K. Eyre, B. Milani, R. van Heeswijk, M. Stuber Lausanne University Hospital, Lausanne, Switzerland Impact: Leveraging inter-bin motion compensation in the free-running framework with lower spatial resolution enables rapid, high-quality, free-breathing cardiac MRI in under 2.5 minutes without compromising left ventricular ejection fraction measurement accuracy. This advancement may enhance clinical workflows and improve patient comfort.
13:15		1281. Large-scale High-Dimensional Image Reconstruction via Delayed and Distributed Computing with BART View Presentation Video M. Blumenthal, M. Uecker Graz University of Technology, Graz, Austria Impact: BART is a versatile toolbox for MRI reconstruction that is widely used due to its flexibility and performance. It is now more memory-efficient and supports distributed computing on multiple GPUs and nodes, allowing researchers to explore even higher-dimensional datasets.
13:15		1282. Benchmarking Gradient Impulse Response Function (GIRF) Acquisition Strategies with Open-Source Measurement Software. View Presentation Video M. Loecher, D. Ennis Stanford University, Stanford, United States Impact: We developed an open-source package (github.com/mloecher/GIRFbench) to acquire, process, and benchmark GIRF measurement strategies to better standardize and understand these techniques. Estimated GIRFs reduced PC-MRI background velocity errors to ≤0.4% of VENC and corrected spiral trajectories to within ∆k=0.31 m-1.

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