ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

ISMRM & ISMRT 2025 Annual Meeting & Exhibition

Oral

Breast MR Advances

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Breast MR Advances
Oral
Body
Tuesday, 13 May 2025
316B
13:30 -  15:30
Moderators: Ziwei Zhao & Sarah Eskreis-Winkler
Session Number: O-20
No CME/CE Credit
13:30 0547. Multiparametric MRI Radiomics for Noninvasive Prediction of HER2-Zero, -Low, and -Positive Breast Cancers
T. Zhan, J-k Dai, J. Shi, C-h Lu
Department of Radiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China
Impact: Multiparametric MRI radiomics has the potential to provide a noninvasive tool for identifying HER2-zero, HER2-low, and HER2-positive in breast cancer patients, thus enabling guide the selection of HER2-targed antibody-drug conjugates.
13:42 0548. Radiogenomics Analysis of DCE-MRI Textures for Tracking Tumor Response and Uncovering Biological Processes in HER2-Negative Breast Cancer
X. Teng, Q. Lai, X. Zhang, J. Zhang, W. Liao, C. Liu, H. Xiao, D. Zhou, D. Hu, T. Li, J. Cai
The Hong Kong Polytechnic University, Hong Kong, Hong Kong
Impact: DCE-MRI effectively tracks breast tumor response by analyzing vascularization and the extracellular matrix. Specifically, mid-treatment scan measuring texture entropy of dependence count optimally predict pathologic complete response, exhibiting exclusive linkage to biological pathways such as angiogenesis and TGF-beta signaling.
13:54 0549. Prediction of breast cancer recurrence based on automatically extracted quantitative MR features
J. Kang, D. Bak, Y. Nam, G. E. Park, S. H. Kim
Hankuk university of Foreign Studies, Yongin-si, Korea, Republic of
Impact: We suggested a cancer recurrence prediction model using breast MRIs from over 1,600 subjects, employing an automated feature extraction process to investigate its feasibility. Additionally, incorporating features from both the ipsilateral and contralateral sides demonstrated an improvement in predictions.
14:06 0550. MR Elastography for early prediction of neoadjuvant chemotherapy efficacy in breast cancer
A-S van Schelt, L. Luque, A. Sinha, B. Shifa, O. Darwish, P. Jurrius, C. Gillet, M. Parsons, A. Purushotham, R. Sinkus
Kings College London, London, United Kingdom
Impact: MRE has a strong predictive potential and offers a non-invasive method for early assessment of neoadjuvant chemotherapy efficacy in breast cancer using dynamic changes of the phase-angle determined at pre-treatment and after the first cycle of chemotherapy.
14:18 0551. Accuracy of OPTIMIST trial criteria on MRI to predict pathologic complete response following neoadjuvant systemic therapy
H. YOEN, N. H. Han, N. Cho, J-J Jung, J. Paggao, H-K Kim, H-B Lee
Seoul National University Hospital, Seoul, Korea, Republic of
Impact: Incorporating the MRI size, SER, and calcification size for accurate pCR prediction supports designing de-escalation trials in good NST responders.
14:30 0552. Intravoxel Incoherent Movement-Based Habitat Imaging for the Prediction of Immunohistochemistry in Patients with Breast Cancer
A. Wang, M. He, M. Ma, Y. Song, C. Wang, G. Yang
Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China
Impact: Besides the prediction results, habitat imaging can better depict the heterogeneity of tumors with clearer biological significance of features used, which might help radiologists to accept or reject model’s prediction on the immunohistochemistry more readily.
14:42 0553. Biomechanical parameters for predicting response to neoadjuvant chemotherapy and disease-free survival in breast cancer
X. Wang, T. Yin, J. Zhang
chongqing university cancer hospital, chongqing, China
Impact: Combining biomechanical parameters quantified by multifrequency MR elastography and clinicopathologic variables showed good performance for predicting pathologic complete response and disease-free survival in breast cancer treated with neoadjuvant chemotherapy.
14:54 0554. Modified BI-RADS with high-resolution DWI: comparison with high-resolution contrast-enhanced imaging in different scanners and cohorts
R. Ota, A. Ikeda, S. Kanao, M. Kataoka, M. Iima, M. Honda, M. Suzuki, N. Kanamori, H. Yamashiro, N. Morii, T. Kubo, Y. Nakamoto
Tenri Hosipital, Nara, Japan
Impact: The result underpins the potential use of HR-DWI as a substitute of HR-CE.
15:06 0555. Multi-Center Optimization of Breast DWI: Comparative Analysis of Fat Suppression Methods (STIR vs. SPAIR) and B-values (800 vs.1500 s/mm2)
E. Inoue, M. Iima, Y. Tokuda, M. Kataoka, K. Yamaguchi, A. Ohashi, T. Ueguchi, H. Satake, K. Ichikawa, Y. Kato, Y. Koyama, Y. Kumano, S. Yamada, R. Sawaya, M. Honda, K. Kubota, K. Ohashi, T. Fujioka, T. Ishimori, S. Naganawa, Y. Nakamoto
Medical Research Institute Kitano Hospital, Osaka, Japan
Impact: STIR and SPAIR show comparable performance in breast DWI, but SPAIR may better visualize small lesions.
15:18 0556. Improving Breast Cancer Diagnosis by Incorporating Transcytolemmal Water Exchange in Time-dependent Diffusion MRI
F. Liu, L. Wu, X. Luo, S. Li, Y. Wang, T. Feiweier, H. Bao, D. Shi, J. Xu, H. Guo
Center for Biomedical Imaging Research, School of Biomedical Engineering, Tsinghua University, Beijing, China
Impact: Our findings proved that transcytolemmal water exchange impact breast cancer diagnosis, highlighting the importance of model selection of time-dependent diffusion MRI tailored to a specific clinical task.
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