ISMRM25 - Perfusion & Function

ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

Perfusion & Function

Oral

Cardiovascular

Wednesday, 14 May 2025

313A

15:45 - 17:45

Moderators: Delphine Périé-Curnier & Masaki Ishida

Session Number: O-29

CME Credit

15:45		1025. Fatty acid composition MRI at 1.5T identifies novel epicardial adipose tissue biomarkers of impaired myocardial perfusion in women with ANOCA View Presentation Video J. Echols, N. Hosadurg, S. Wang, B. Paudel, A. Patel, P. Rodriguez Lozano, F. Epstein University of Virginia, Charlottesville, United States Impact: This study introduces EAT FAC imaging at 1.5T as a potential mechanism of microvascular dysfunction to further investigate in women with ANOCA.
15:57		1026. MRI of early myocardial ischemia in a pig model and feasibility of MR-guided balloon occlusion for real-time time ischemia imaging View Presentation Video S. Reiss, D. Boll, T. Heidt, C. von zur Muehlen, A. Maier, M. Bock University Medical Center Freiburg, University of Freiburg, Freiburg, Germany Impact: This study provides a detailed assessment of CMR findings of early reperfusion injury and demonstrates, that MR-guided coronary balloon occlusion is feasible. This may enabling real-time imaging of myocardial injury formation.
16:09		1027. Accelerated 4D DENSE for Volumetric Myocardial Strain Imaging Using Reduced Field-of-View: A Preliminary Study View Presentation Video Y. Wu, S. Wang, S-F Shih, S. Li, F. Han, K-L Nguyen, J. finn, X. Zhong University of California Los Angeles, Los Angeles, United States Impact: The accelerated protocol achieved a reliable 33% reduction in acquisition time compared to the reference protocol. With further optimization and validation, this proposed network may facilitate efficient 4D DENSE data acquisition for whole-heart strain imaging in clinical settings.
16:21		1028. ASL-CMR detects coronary microvascular dysfunction in diabetic mice: a multi-imaging modality comparison View Presentation Video Q. Miao, Y. Shi, B. Li, R. Luo, C. Liu, H. Liao, W. Peng, H. Qi ShanghaiTech University, Shanghai, China Impact: ASL-CMR enables early detection and quantitative assessment of coronary microvascular dysfunction (CMD) in diabetes as validated against histology, which may server as a useful tool for monitoring CMD progression and evaluating therapeutic interventions without contrast agents or radiation exposure.
16:33		1029. Accurate Coronary Sinus MR Oximetry with Auto-Hematocrit Calibration - Proof of Concept Study in Pigs with Invasive Validation View Presentation Video C. C. Yang, A. Malagi, L-T Huang, Y. Huang, G. Yoosefian, X. Zhang, X. Guan, A. G. Christodoulou, D. Li, H. Han, R. Dharmakumar, H-j Yang Cedars Sinai Medical Center, Los Angeles, United States Impact: The proposed free-breathing, multiparametric, self-calibrated MR Oximetry can accurately measure HCT in the coronary sinus. It can help with precise noninvasive blood characterization in deep vessels and be adapted to other MRI parameters (e.g., extracellular volume) that require HCT measurements.
16:45		1030. Advances in free-breathing 3D cardiac MR elastography via TURBINE-MRE View Presentation Video N. Meyer, Y. Sui, J. Magnuson, P. Rossman, K. Glaser, M. Murphy, A. Manduca, I. Chang, K. McGee, K. Kantarci, E. Kapoor, P. Araoz, R. Ehman, J. Trzasko, A. Arani Mayo Clinic, Rochester, United States Impact: MRI-derived measures of myocardial mechanical properties have important clinical and scientific applications, but are predominantly measured with breath-held scans and limited geometries, or invasively. This work demonstrates free-breathing elastography of the whole heart, enabling broader application and analysis.
16:57		1031. Unsupervised whole-heart function assessment View Presentation Video Y. Zhang, D. Rueckert, J. Pan Technical University of Munich, Munich, Germany Impact: This method offers a scalable approach for cardiac screening by creating a latent space as well as distinct time-segment embeddings, enabling diverse preliminary analysis of cardiac function and potentially advancing research in cardiovascular disease applications.
17:09		1032. Clinical Validation of a Wideband Perfusion Pulse Sequence: Myocardial Blood Flow Quantification in Patients with a CIED during stress and at rest View Presentation Video L. Fan, D. Bishara, M. Jimenez, J. Urban, K. Hong, J. Collins, L-Y Hsu, S. Wang, A. Patel, C. Topel, O. Aboyewa, D. Lee, D. Kim Northwestern University Feinberg School of Medicine, Chicago, United States Impact: This study validates that a 6-fold accelerated wideband perfusion pulse sequence produces meaningful stress MBF and MPR measurements for detecting myocardial ischemia in patients with ICDs.
17:21		1033. Metabolic phenotypes and cardiac function: Insights from UK Biobank cardiac MRI and outcomes analysis View Presentation Video B. Bogner, M. Jung, M. Reisert, J. Maushagen, S. Rospleszcz, J. Nolde, C. Schlett, F. Bamberg, A. Kammerlander, J. Weiss, J. Taron University Medical Center Freiburg, Freiburg , Germany Impact: This large-scale analysis reveals unique cardiac phenotypes across metabolic categories, providing new insights for early cardiovascular risk assessment in metabolically diverse populations.
17:33		1034. End-to-End Nonrigid MOtion COrrected DEep Learning Spiral Image REconstruction (MOCO-DESIRE) for free breathing perfusion imaging View Presentation Video Q. Chen, J. Wang, X. Wang, S. Zhao, S. Liu, M. Salerno1 Stanford University, Palo Alto, United States Impact: This approach obtains high-quality motion corrected perfusion images within seconds, facilitating the possibility of on-line imaging.

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