ISMRM25 - Diffusion on Unconventional Systems

ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

Diffusion on Unconventional Systems

Oral

Diffusion

Monday, 12 May 2025

323AB

16:00 - 18:00

Moderators: Elizabeth Huaroc Moquillaza & Yuichi Suzuki

Session Number: O-39

No CME/CE Credit

16:00		0313. Human Gradient Breast Coil: Approach for Filter Exchange Imaging with Ultra-High Gradient Amplitude View Presentation Video P. Jimenez, S. Littin, F. Jia, R. Umathum, F. B. Laun, M. E. Ladd, S. Bickelhaupt, M. Zaitsev, T. Kuder German Cancer Research Center (DKFZ), Heidelberg, Germany Impact: The local gradient breast coil enabled AXR measurements with reduced echo times by utilizing extreme gradient amplitudes and slew rates, demonstrating the potential of the coil to increase SNR, extend DWI parameter space coverage and thereby improve breast cancer imaging.
16:12		0314. Scan-Rescan Repeatability of Axon Diameter Mapping Metrics from Ultra-High-Gradient Diffusion MRI on the Connectome 2.0 Scanner View Presentation Video L. Eskandarian, Y. MA, H. Lee, K-S Chan, A. Bhatt, J. Gerold, S. Y. Huang Mass General Hospital, Boston, United States Impact: This research enhances the understanding of diffusion-MRI metrics' reliability, enabling more accurate studies of brain microstructure. It supports further investigation into neurobiological differences across populations and potential clinical applications.
16:24		0315. Undercooked PASTA: Tractometry at low field and low SAR View Presentation Video J. Gholam, J. Ametepe, N. Wiley, S. Kolind, S. Balaji, F. Padormo, M. Cercignani, D. Jones CUBRIC, School of Psychology, Cardiff University, Cardiff, United Kingdom Impact: Ultra-low-field MR systems offer unprecedented opportunity to access populations otherwise excluded from scanning by location or means. This work demonstrates that traditional high-field tractometry is possible at 0.064T within a feasible scan duration in healthy adults
16:36		0316. Comparative Evaluation of Third-Order Motion-Compensated DT-CMR Across Cardiac Phases Using an Ultra-High-Performance Clinical Scanner View Presentation Video K. Wen, P. Ferreira, R. Wage, K. Kunze, D. Pennell, A. Scott, S. Nielles-Vallespin Imperial College London, London, United Kingdom Impact: We conducted the first in-human evaluation of M3-MCSE for diastolic imaging, comparing it with STEAM and M2-MCSE across various cardiac phases. Findings suggest the importance of further optimising higher-order motion compensation with shorter TE to enhance MCSE clinical potential.
16:48		0317. Human brain high-resolution OGSE diffusion MRI with slice-by-slice B0 shimming in an ultra-high performance gradient 3T MRI system View Presentation Video P. Lan, S. Huang, G. Wu, R. Huang, J. Maller, J. McNab, T. Foo, S-K Lee, A. Zhu GE HealthCare, Menlo Park, United States Impact: MRI-based tissue microstructure imaging can benefit from the fast, high-quality, time-dependent diffusion MRI with the optimized dynamic linear slice-by-slice B₀ shimming technique that is applicable to any MRI system.
17:00		0318. Ultrahigh-resolution, whole-brain MAP-MRI in vivo using the NexGen 7T scanner View Presentation Video A. Avram, A. Vu, K. Magdoom, A. Beckett, D. Feinberg, P. Basser National Institutes of Health, Bethesda, United States Impact: Ultrahigh resolution MAP-MRI could improve the neuroradiological assessment of cortical and subcortical gray matter and the early detection of neurodegenerative diseases. It could enable direct segmentation of cortical cytoarchitectonic domains and advance our ability to map connections between cortical layers.
17:12		0319. Cartesian MaxGIRF: Model-based EPI reconstruction incorporating gradient nonlinearity and concomitant field effects View Presentation Video N. Lee, S. Cui, K. Nayak University of Southern California, Los Angeles, United States Impact: Standard corrections for gradient nonlinearity and off-resonance have detrimental effect on image quality and on quantitative diffusion measures. The proposed framework performs all corrections during image reconstruction and provides better image quality by avoiding the smoothing effect of interpolation-based corrections.
17:24		0320. Optimizing Diffusion Tractography Imaging with Clinically-Practical Acquisition Times on Portable, Low-Field MRI View Presentation Video A. Sorby-Adams, M. Olchanyi, J. Kirsch, A. Farnan, M. Rosen, E. Brown, B. Edlow, J. E. Iglesias, W. T. Kimberly Massachusetts General Hospital and Harvard Medical School, Boston, United States Impact: Portable, low-field diffusion MRI could aid in the assessment of white matter integrity and diagnosis of neurologic disorders in regions/facilities lacking access to conventional MRI, and in clinically unstable patients unable to be transported to a centralized neuroimaging suite.
17:36		0321. Accurate super-resolution of diffusion MRI data at ultra-strong gradients and varying diffusion time using Image Quality Transfer View Presentation Video E. Lupi, F. Palesi, C. McNabb, P. Luque Laguna, M. Figini, D. Alexander, E. D’Angelo, C. Gandini Wheeler-Kingshott, M. Cercignani, M. Palombo University of Pavia, Pavia, Italy Impact: We demonstrated IQT effectiveness in advanced DWI acquisitions with ultra-high b-values and multiple diffusion times when adapted with suitable signal representation. This approach advances the precise study of brain microstructure, overcoming current DWI limitations in both clinical and research settings.
17:48		0322. High Resolution Diffusion MRI Tractography in the in-vivo & ex-vivo NHP brain using a human 10.5T scanner View Presentation Video S. Warrington, B. Tendler, M. Kotb Selim, W. Wu, H. Farooq, S. Moeller, P. Pisharady, E. Auerbach, G. Adriany, A. Bratch, M. Waks, S. Jungst, N. Harel, F. Pestilli, S. Heilbronner, E. Yacoub, K. Ugurbil, C. Lenglet, K. Miller, S. Jbabdi, J. Zimmermann, S. Sotiropoulos Sir Peter Mansfield Imaging Centre, School of Medicine, University of Nottingham, UK, Nottingham, United Kingdom Impact: We showcase for the first time the performance of the 10.5T human whole-body MRI scanner at the CMRR, University of Minnesota, for high-resolution diffusion MRI and tractography in the in-vivo and ex-vivo macaque brain.

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