ISMRM25 - Novel Diffusion Acquisition & Reconstruction Methods

ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

Novel Diffusion Acquisition & Reconstruction Methods

Oral

Diffusion

Tuesday, 13 May 2025

311

13:30 - 15:30

Moderators: William Grissom & Nan Wang

Session Number: O-41

No CME/CE Credit

13:30		0508. 387μm isotropic resolution in-vivo diffusion MRI using Romer-EPTI on Connectome 2.0 scanner View Presentation Video F. Wang, J. Wu, T. Reese, H-H Lee, B. Rosen, S. Huang, L. Wald, Z. Dong Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, United States Impact: We achieved in-vivo dMRI at 387-um-isotropic resolution with whole-brain coverage by leveraging SNR-efficient distortion-free Romer-EPTI acquisition, ultra-high-gradient-performance Connectome 2.0 scanner, and correction techniques that address strong concomitant and eddy-current fields caused by the strong gradients.
13:42		0509. Metal Artifacts Suppression in Diffusion Imaging Using Point-Spread-Function Encoded EPI View Presentation Video S. Li, Y. Wang, Z. Hu, X. Han, H. Zhang, L. Guan, Y. Hai, H. Guo Center for Biomedical Imaging Research, Tsinghua University, Beijing, China Impact: The metal artifacts in DWI can be effectively reduced using our proposed reconstruction method for highly accelerated PSF-EPI. This benefits the post-operative evaluations of patients with spinal fusions and allows high-resolution (1.0×1.0 mm²), large-coverage DWI within clinically feasible scan time.
13:54		0510. Multi-site Quality Assurance of Diffusion and Fat-Water Imaging for Neuromuscular Applications: A Phantom Study View Presentation Video P. Wang, X. Ma, Y. Chen, R. Dortch Barrow Neurological Institute, Phoenix, United States Impact: Our findings demonstrate that quality assurance can be effectively maintained across the three MRI systems, ensuring reliable and accurate DWI and PDFF measurements, which is crucial for our multi-site studies.
14:06		0511. End-to-end Complex Image Reconstruction Pipeline for GE Diffusion MRI Acquisitions View Presentation Video F. D'Antonio, S. Warrington, P. Morgan, S. Sotiropoulos Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom Impact: The offline reconstruction pipeline allows access to complex dMRI data, retrospectively switching filters off and supporting in-plane/out-of-plane accelerations and partial Fourier. This allows seamless operations in the complex domain (e.g. denoising) and potentially paves the way for vendor-agnostic image reconstruction.
14:18		0512. Improving signal homogeneity of whole-brain DWI at 7T with universal multiband GRAPE pTx pulses View Presentation Video M. Veldmann, D. Löwen, T. Stöcker DZNE, Bonn, Germany Impact: Universal slice-selective GRAPE pTx pulses in multiband whole-brain DWI at 7T significantly improve signal homogeneity in the brain and signal intensity in the cerebellum, while being robust to moderate slice tilts. This enables their routine use in neuroscientific studies.
14:30		0513. Rapid implicit Spatio-Temporal Field Estimation and Correction for Diffusion MRI (D-FESTiVE) View Presentation Video Z. Shah, D. Abraham, N. Wang, C. Liao, Q. Liu, L. Ning, Y. Rathi, A. Kerr, K. Setsompop Stanford University, Stanford, United States Impact: We propose an alternative to field probes for eddy-current characterization in dMRI executable as a rapid pre-scan calibration. This will enable enhanced image reconstruction at high b-value without external hardware, enabling high-resolution fast imaging of brain connectivity and microstructure.
14:42		0514. Phase Reversed Interleaved Multi-Echo (PRIME) with phase, field map and motion navigators for highly accelerated distortion-free diffusion MRI View Presentation Video Y. Jun, Q. Liu, T. Gong, J. Cho, S. Fujita, X. Yong, S. Huang, L. Ning, A. Yendiki, Y. Rathi, B. Bilgic Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, United States Impact: We propose a highly accelerated distortion-free dMRI sequence, which can achieve 490μm isotropic resolution with high-fidelity field maps, shot-to-shot phase, and motion correction from additional echoes without prolonging repetition time when gSlider RF encoding is used.
14:54		0515. In-vivo submillimeter 3D diffusion MRI for high-resolution, SNR-efficient microstructure imaging View Presentation Video Z. Li, S. Zhu, K. Miller, W. Wu University of Oxford, Oxford, United Kingdom Impact: Our study achieves in-vivo submillimeter whole-brain 3D dMRI with minimal blurring, distortion and high SNR. Our approach holds promise in broadly providing more detailed depictions on human brain microstructure and connectivity.
15:06		0516. HERON: High-Efficiency Real-Time mOtion quantification and re-acquisitioN for Fetal dMRI View Presentation Video J. Aviles Verdera, A. Bortolazzi, S. Neves Silva, K. St Clair, S. McElroy, S. Ourselin, R. Tomi-Tricot, M. Rutherford, J. Hajnal, J. Hutter King's College London, London, United Kingdom Impact: Enhancing fetal diffusion MRI through an automatic AI-driven pipeline enabling automatic planning, real-time quality checks and prospective re-acquisition of corrupted volumes enables higher diagnostic quality and wider use.
15:18		0517. Diffusion MRI with a Multi-Shot Rosette Readout View Presentation Video K. Harkins, J. Martin, M. Does Vanderbilt University Medical Center, Nasvhille, United States Impact: This abstract demonstrates multi-shot rosette readouts in diffusion MRI, including using redundant k-space information for estimating B₀ and phase variations to improve image quality, evaluated in ex vivo ferret brains and in vivo mouse spinal cord.

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