Oral
Body Diffusion MRI: Applications
ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i
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Introduction |
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0889. A
REnal Flow and Microstructure AnisotroPy (REFMAP) MR assessment
of renal function: comparison with measured glomerular
filtration rate
N. Gilani, N. Jeet, W. Huang, V. Tatapudi, F-M Deng, K.
Friedman, K. Soltys, M. Bruno, M. Kumbella, S. Nagpal, H.
Chandarana, E. Sigmund
NYU Langone Health, New York, United States
Impact: We present a diffusion-weighted MR method to
assess the function of individual kidneys in a cohort of
kidney cancer patients. The technique outputs accurate
information complementary to routinely used estimated
glomerular filtration rate (eGFR).
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| 13:54 |
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0890. Differentiating
Benign and Malignant Thyroid Nodules Using Time-Dependent
Diffusion MRI
H. Ren, Z. Wang, J. Zhang, D. Shi, D. Liu, H. Guo, J. Xu, J.
Huang, H. Yu, Y. Tan, T. Yin
Chongqing University Cancer Hospital, Chongqing, China
Impact: The combined model integrating apparent
diffusion coefficient and microstructural parameters
microstructural parameters based on td-dMRI holds potential
to differentiate between benign and malignant thyroid
nodules. This distinction is critically important for the
diagnosis and management of thyroid nodules.
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| 14:06 |
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0891. Restricted
Diffusion Volume (RDV): a novel quantitative metric to improve
prediction of breast cancer response to neoadjuvant chemotherapy
P. Bolan, D. Biswas, G. Metzger, A. Kazerouni, W. Li, L.
Wilmes, J. Gibbs, A. Church, N. Hylton, S. Partridge
University of Minnesota, Minneapolis, United States
Impact: RDV is a novel, semi-automated diffusion metric
that provides improved performance over conventional
ROI-mean ADC. This can be used to optimize treatment and
could lead to contrast-free therapy monitoring.
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| 14:18 |
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0892. The
value of diffusion-derived vessel density (DDVD) in
differentiating hepatocellular carcinoma and liver hemangioma
J. Yu, L. Liu, J. Guo, D. Luo, Z. Liu
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, 518116, China, Shenzhen, China
Impact: Diffusion-derived vessel density, a novel
imaging biomarker reflecting tissue vessel density, holds
the potential to visualize spatial angiogenesis
heterogeneity and enhance diagnostic accuracy in
distinguishing between hepatocellular carcinoma and
hemangioma, enabling more precise treatment planning and
improved patient outcomes.
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| 14:30 |
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0894. Restriction-weighting
in tensor-valued diffusion encoding: A novel experimental
framework demonstrated in human prostate cancer xenograft
M. Molendowska, S. Lasič, J. Strand, F. Szczepankiewicz
Lund University, Lund, Sweden
Impact: We propose an experimental design and analysis
of tensor-valued diffusion encoding that incorporates
effects of restricted diffusion. The results shed light on
confounding effects of restricted diffusion in tensor-valued
encoding experiments with mixed encoding frequencies.
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| 14:42 |
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0895. Time-Dependent
Diffusion MRI in the diagnosis of Prostate Cancer
B. Zhou, X. Liu, C. Fu, H. Lv, L. Zhou, Y. Gu
Fudan University Shanghai Cancer Center, Shanghai, China
Impact: OGSE has more advantages than PGSE in the
diagnosis of prostate cancer, with ADC17Hz performing
the best. All parameters of OGSE and PGSE were correlated
with GS.
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| 14:54 |
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0896. A
multivariate model of IVIM-DWI in preoperative diagnosis of
tumor budding grade in rectal cancer
J. Fu, C. Zhao, G. Song, G. Zheng, D. Pylypenko, A. Li
Department of Radiology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Lung Cancer Institute, Shandong Institute of Neuroimmunology, Jinan, China
Impact: This study highlights the potential of combining
multi b-value DWI-IVIM with clinical features for
non-invasive preoperative grading of tumor budding in rectal
cancer, enabling more personalized treatment strategies and
improving prognostic accuracy for patient outcomes.
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| 15:06 |
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0897. Diagnostic
Value of Time-Dependent Diffusion MRI in Differentiating
Endometrial Cancer
J. Yang, Q. Bi, M. Chen, T. Feiweier, B. Wang
The First People’s Hospital of Yunnan Provence, Kunming, China
Impact: Time-dependent diffusion MRI can non-invasively
reveal microstructural characteristics of endometrial
cancer, potentially improving diagnostic accuracy and
informing preoperative planning, which may reduce invasive
procedures and enhance treatment decision-making.
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| 15:18 | 0893. WITHDRAWN |
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