ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

ISMRM & ISMRT 2025 Annual Meeting & Exhibition

Oral

fMRI Analysis & Connectivity

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fMRI Analysis & Connectivity
Oral
fMRI
Thursday, 15 May 2025
313A
15:30 -  17:30
Moderators: Laura Lewis & Pinar Ozbay
Session Number: O-49
CME Credit
15:30 1343. The Primary-association Gradient across the Human Lifespan
Q. Li, L. Sun, D. Zeng, X. Liang, M. Xia, S. Li, Y. He
Beijing Normal University, Beijing, China
Impact: Results advance our understanding of the lifespan changes in topographic organization of the human brain and its impact on cognitive spectrum.
15:42 1344. A data-driven definition of metastable brain states and trajectories characterizes group differences in various brain processes
M. Sourty, L. Dormegny-Jeanjean, J. Bahuguna, A. Moreau, D. Battaglia, J. Foucher
ICube laboratory, University of Strasbourg, FMTS, Strasbourg, France
Impact: Reproducibility of these highly segregated brain configurations between subjects supports the adequacy of models describing brain dynamics as transitions in a multistable state-space. Our method comes with an appealing temporal resolution to study pathological or/and individual brain activity trajectories.
15:54 1345. Intra- and inter-regional neural activity synchronizations drive rsfMRI network dynamics upon single thalamic input
L. Xie, X. Wang, X. Lin, J. Wen, A. T. L. Leong, E. X. Wu
The University of Hong Kong, Hong Kong SAR, China
Impact: Our results provide the first direct delineation and validation of rsfMRI network dynamics that enable prompt and flexible network reconfiguration to facilitate effective processing of any neural information input. 
16:06 1346. The default mode network is causally involved in memory retrieval and network integration plays a key role in this process
Z. Li, D. Athwal, K-H Chuang
The University of Queensland, Brisbane, Australia
Impact: Our results show that DMN plays a causal role in memory processes, emphasizing the importance of network integration for memory. These findings enhance our understanding of DMN's involvement in higher-order cognition and offer potential measurement methods for various brain disorders.
16:18 1347. Connectome caricatures: large-amplitude co-activation patterns in resting-state fMRI hide sources of individual differences
R. Rodriguez, S. Noble, C. Camp, D. Scheinost
Yale University, New Haven, United States
Impact: A distinct signal carrying information about individual differences exists beyond the dominating co-activations that drive resting-state functional connectivity. This signal may better characterize the brain’s intrinsic functional architecture and can be used to evaluate novel sources of individual differences.
16:30 1348. Detection of white and gray matter functional networks in the human cervical spinal cord at 7T using resting-state BOLD fMRI
J. Polcari, A. Sengupta, A. Witt, S. Smith, R. Barry, L. M. Chen, J. Gore
Vanderbilt University Medical Center, Nashville, United States
Impact: ICA of 7T human spinal cord fMRI revealed new functional networks being robustly detected within GM and WM of cervical SC which will help in better understanding the sensorimotor integration of information within the SC and thus have clinical significance.
16:42 1349. Brain-wide spatiotemporally distinct traveling waves drive anxiety-like behaviors in mice
J. Liu, J-W Mo, X. Wang, Y. Ma, P-L Kong, Z. An, L. Ding, J. Ren, C-L Lu, C. Tong, E. X. Wu, Q-g Hu, X. Cao, Y. Feng
Department of Radiology, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde), Foshan, China
Impact: Our study provide brain-wide view of the traveling wave propagation and reveals their functional role in inducing anxiety.
16:54 1350. Optogenetic-silencing mouse fMRI reveals spontaneous neural activity propagating through polysynaptic structural connectivity
H. S. Moon, S-G Kim
Center for Neuroscience Imaging Research, Institute for Basic Science (IBS), Suwon, Korea, Republic of
Impact: This study aimed to elucidate the relationship between resting-state functional connectivity and causal neural interactions assessed by optogenetic fMRI, with a specific focus on the role of polysynaptic structural pathways.
 
17:06 1351. layerfMRI-toolbox helps to automatize high-resolution whole-brain layer segmentation in volume space with minimum manual editing.
M. Barilari, K. Koiso, P. Taylor, O. Gulban, D. Glenn, P. Bandettini, O. Collignon, R. Huber
Universitè Cathoulique de Louvain, Louvain-La-Neuve, Belgium
Impact: We proposed an easy to use software toolbox that can standardize and streamline layer-fMRI analyses. It is scalable across large N studies with minimal necessity for manual corrections.
17:18 1352. Biophysical simulations using realistic Vascular Anatomical Networks predict BOLD response attenuation at high stimulation frequencies
G. Hartung, D. Gomez, J. S. Proulx, J. Polimeni
Technical University of Darmstadt, Wetter, Germany
Impact: The role of vascular anatomy in BOLD responses attenuation at higher-frequency sensory stimulation is unclear. We apply biophysical modeling to investigate whether the cerebral cortical microvascular network influences BOLD dynamics and generates discrepancies between blood volume and oxygenation responses.
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