ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

ISMRM & ISMRT 2025 Annual Meeting & Exhibition

Oral

Technical Developments in Musculoskeletal MRI

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Technical Developments in Musculoskeletal MRI
Oral
Musculoskeletal
Thursday, 15 May 2025
316C
08:15 -  10:15
Moderators: Erin Englund & Emily McWalter
Session Number: O-52
No CME/CE Credit

08:15 1154. Accelerated T1ρ and T2 High Resolution Imaging: a Multi-vendor Multi-site study
Z. Zhang, J. Kim, R. Liu, R. Latery, C. Winalski, M. Yang, J. Liu, T. Link, Q. Peng, M. Samaan, P. Hardy, L. Ying, X. Li
Cleveland Clinic, Cleveland, United States
Impact: We demonstrated  high-resolution fast cartilage relaxometry imaging is reliable and reproducible, with excellent agreement between reference and accelerated imaging, excellent scan-rescan repeatability, and consistency across sites and vendors. Such techniques will greatly facilitate the clinical translation of quantitative knee imaging. 
08:27 1155. DCEMRI Modelling in the Presence of Ill-perfused Regions
J. Waterton, J. Naish, A. Mahmutovic, L. Edwards, M. Heaton, M. Tibiletti, L. Nordenmark, G. Parker, J. MacKay
Bioxydyn, MANCHESTER, United Kingdom
Impact: A robust DCEMRI analysis with better face validity increases confidence in the pathophysiologic interpretation of any pharmacodynamic changes.  
08:39 1156. Simultaneous solid and multiple-contrast soft tissue musculoskeletal magnetic resonance imaging
E. Baccaglini, B-T Vu, N. Kamona, F. Wehrli, C. Rajapakse
University of Pennsylvania, Philadelphia, United States
Impact: DREAMER performs simultaneous imaging of musculoskeletal solid and soft tissues, potentially obviating the need for additional CT. It can reduce the use of ionizing radiation in clinical imaging and remove logistical complexities related to scheduling examinations.
08:51 1157. A new technique for detecting waves parallel to muscle fibers in MR elastography: Application to the supraspinatus muscle
D. Ito, T. Numano, T. Habe, T. Nozaki, Y. Ishihara, J. Tsuzaki, M. Hase, M. Arai, M. Jinzaki
Keio University Hospital, Tokyo, Japan
Impact: Our technique enhances the reliability of skeletal muscle MRE by extracting waves along the muscle fiber direction and automating stiffness measurements. This advancement enables accurate assessment of pathological and physiological changes, supporting early diagnosis and better assessment of musculoskeletal disorders.
09:03 1158. NAD in skeletal muscle at 3 T: impact of age and disease
H. Reyngoudt, B. Matot, V. Henriet, Y. Fromes, B. Marty
Institute of Myology, Paris, France
Impact: Since NAD is abundant in living cells and sensitive to change (age, disease, exercise, supplementation) and 31P MRS allows its quantification, this metabolite can serve as a potential quantitative MR biomarker in skeletal muscle studies.
09:15 1159. Cartesian vs. non-cartesian under-sampling for high resolution 3D double echo steady state (DESS) knee imaging at 7 T
T. Marth, A. Marth, G. Kajdi, D. Paul, R. Sutter, D. Nanz, C. von Deuster
Balgrist Campus AG, Zurich, Switzerland
Impact: The results suggest significant advantages of non-cartesian versus cartesian undersampling strategies in DESS imaging with high acceleration factors at 7T. The short acquisition times may allow clinical high-resolution 3D knee cartilage imaging, e.g., for quantification of cartilage morphology.
09:27 1160. Advanced In-Vivo 3D Quantitative Magnetization Transfer Imaging of Cartilage Extracellular Matrix of the Whole Knee Joint
A. Jang, Z. Stewart, M. Jarraya, F. Liu
Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, United States
Impact:

BTS showed spatial variation and regional features of qMT parameters in a healthy model, presenting great potential in providing 3D relaxometry and qMT imaging biomarkers to characterize whole knee cartilage extracellular matrix, which requires further investigation using groupwise analysis.

09:39 1161. Cartilage shape-informed 3D gray level co-occurrence matrix analysis of DESS T2 maps
V. Janacova, P. Szomolanyi, D. Sitarcikova, S. Trattnig, V. Juras
Medical University of Vienna, Vienna, Austria
Impact: This study demonstrates the high repeatability of cartilage shape informed 3D GLCM features. Since cartilage structure varies in directions perpendicular and parallel to the bone-cartilage interface, accurately assessing texture in these anatomically relevant orientations is clinically important.
09:51 1162. Fast Three-Dimensional Short TR Adiabatic Inversion Recovery Ultrashort Echo Time (STAIR-UTE) Imaging of Cortical Bone
M. Daskareh, M. Carl, A. Suprana, J. Chen, J. Lo, S. Jerban, E. Chang, C. Chung, Y. Ma, J. Du
UC San Diego, San Diego, United States
Impact: STAIR-UTE allows fast direct imaging of cortical bone at various anatomical sites with high positive contrast, with potential for routine clinical applications
10:03 1163. Optimization and Mechanisms of UTE-Magnetization Transfer (MT) contrast in the ACL
E. Argentieri, M. Han, S. Majumdar, P. Larson
University of California - San Francisco, San Francisco, United States
Impact: These parameters and understanding of MT in the ACL using UTE MRI will be beneficial to better interpret MT measurements as well as for designing improved imaging protocols that will be more sensitive to degeneration.
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