ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

ISMRM & ISMRT 2025 Annual Meeting & Exhibition

Oral

Relaxometry Across Different Tissues

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Relaxometry Across Different Tissues
Oral
Musculoskeletal
Monday, 12 May 2025
313C
08:15 -  10:15
Moderators: Berk Açikgöz & Ananya Goyal
Session Number: O-54
CME Credit

08:15 0056. SGDNet: Synthetic Data Guided Supervised Deep Learning Network for Multi-Component T1$$$\rho$$$ Mapping in the Knee Joint
D. Singh, R. R. Regatte, M. V. W. Zibetti
Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, United States
Impact: Our results indicate that SGDNet is faster for whole knee joint T1$$$\rho$$$ mapping than the NLS-based methods, with comparable errors. Thus, SGDNets is an alternative to replace NLS and RNLS for T1$$$\rho$$$ mapping when computational time is an issue.
08:27 0057. Ultrashort Echo Time Quantitative Susceptibility Source Separation in the Musculoskeletal System: A Feasibility Study
S. Sedaghat, J. Park, E. Fu, A. von Drygalski, D. Moazamian, Y. Ma, E. Chang, J. Du, L. Nardo, H. Jang
University Hospital Heidelberg, Heidelberg, Germany
Impact: UTE-based QSM enables precise separation of paramagnetic and diamagnetic sources in musculoskeletal tissues, improving detection of iron deposits in joints. This technique promises enhanced accuracy in diagnosing conditions like hemophilic arthropathy and assessing biochemical tissue composition in clinical applications.
08:39 0058. Ultra-short-echo time Sequence for Bi-exponential T1ρ Mapping of Achilles Tendinopathy
A. Monga, H. Moura, M. Zibetti, S. Rao, R. Regatte
NYU Grossman School of Medicine, New York, United States
Impact: The study demonstrates that the T1ρ mapping obtained from magnetization-prepared 3D-UTE Sequence can potentially detect AT, particularly with BE relaxation models when combined with LDA.
08:51 0059. The Exploration of Skeletal Muscle Abnormalities in Advanced Chronic Liver Disease using Muscle ECV Measured by T1-mapping MRI
Y. Young
Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, China
Impact: The muscle ECV fraction, quantified by T1-mapping MRI, may help elucidate the pathophysiological mechanisms of skeletal muscle abnormalities in patients with ACLD.
09:03 0060. Water specific T1 in Skeletal Muscle: Validation, Normative Values and the Confounding Influence of Fat
S. Foulkes, M. Haykowsky, R. Sherrington, A. Kirkham, J. Grenier, P. Seres, C. Beaulieu, D. Paterson, R. Thompson
University of Alberta, Edmonton, Canada
Impact: The SR-CSE approach jointly quantifies skeletal muscle fat and water-specific T1 (T1Water, removing T1 bias from fat), offering detection of muscle fibrosis and/or edema with co-existing fatty infiltration (e.g. sarcopenia).
09:15 0061. Free-breathing High-resolution 3D Whole-heart Adiabatic T1ρ Mapping at 0.55T
D. Si, M. Crabb, S. Littlewood, K. Kunze, C. Prieto, R. Botnar
School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom
Impact: The proposed 3D T1ρ mapping sequence demonstrates the feasibility of non-invasive myocardial tissue characterization at 0.55T with 2mm isotropic-resolution in an efficient free-breathing scan of 7 mins. Both phantom and in-vivo 3D T1ρ measurements showed excellent agreements with reference sequences.
09:27 0062. Neural-network-based accelerated liver water T1 mapping
E. Huaroc Moquillaza, V. Spieker, C. Rao, J. Meineke, K. Weiss, J. Schnabel, M. Doneva, D. Karampinos
Institute of Diagnostic and Interventional Radiology, TUM School of Medicine and Health, Department Clinical Medicine, Technical University of Munich, Munich, Germany
Impact: A neural network-based liver wT1 mapping technique that shortens acquisition times using CIR-LL without sacrificing the quality of quantitative reconstruction results, and holds promise for further mapping applications.
09:39 0063. Non-Contrast T1ρ Mapping can Differentiate Hypertrophic Cardiomyopathy from Hypertensive Heart Disease: A Prospective Clinical CMR Study
D. Yang, K. Li, H. Qin, J. Zheng
Department of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning ,China, Nanning, Chile
Impact:

This research employs non-contrast T1ρ mapping to evaluate fibrosis differences between HCM and HHD, providing valuable insights for distinguishing left ventricular hypertrophy, consequently supporting customized, patient-specific treatment approaches.

09:51 0064. Multi-site Multi-vendor Randomized Controlled Trial of Quantitative Knee MRI using a Novel MSK Relaxometry Phantom
J. Kim, Z. Zhang, R. Lartey, M. Li, S. Zbyn, S. Tosun, S. Russek, K. Stupic, C. Stoffer, K. Keenan, D. Rutkowski, J. Kammerman, J. Brittain, C. Winalski, X. Li
Cleveland Clinic, Cleveland, United States
Impact: We established a QA process for knee MRI relaxometry using a novel MSK relaxometry phantom for large-scale multi-site studies. By identifying discrepancies in measurements during the study, the QA process will ensure data quality in multi-site studies.
10:03 0065. Interleaved ultrashort echo acquisition for motion-robust bicomponent imaging of cortical bone
S. H. Shin, J. Lo, A. Suprana, J. Wang, D. Moazamian, D. Berry, S. Jerban, E. Chang, J. Du, Y. Ma
UC San Diego, La Jolla, United States
Impact: The proposed sequence enables motion-insensitive quantitative imaging of short T2 tissues requiring multi-echo acquisitions, such as bi-component T2* imaging and quantitative susceptibility mapping, without post-acquisition motion correction.
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