ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

ISMRM & ISMRT 2025 Annual Meeting & Exhibition

Oral

High-Field MRI

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High-Field MRI
Oral
Physics & Engineering
Monday, 12 May 2025
313A
16:00 -  18:00
Moderators: Mary McDougall & Tom Scheenen
Session Number: O-78
CME Credit
16:00   Introduction
Tom Scheenen
16:12 0263. An ultra-fast RF switch for 23Na SWIFT imaging at 10.5T
R. Lagore, S. Schmidt, E. Auerbach, N. Kobayashi, C. Schildknecht, S. Moeller, G. Adriany, G. Metzger
University of Minnesota, Minneapolis, United States
Impact: Enabling imaging of nuclei with fast relaxation times with custom-built fast-switching PIN drivers and RF frontend which features sub-microsecond switching speeds and isolations of up to 100 dB between transmit and receive.
16:24 0264. Mapping amide protons in the human brain at 3 and 7 Tesla using downfield MRSI
İ. Özdemir, S. Etyemez, P. Barker
Johns Hopkins University, Baltimore, United States
Impact: Amide mapping using DF-MRSI at 7T showed significantly superior precision compared to 3T, and therefore is the preferred field strength for future research studies of DF metabolites.
16:36 0265. Imaging of the Entire Spinal Cord with a 32-Channel pTx Body Array at 7 T
C. Aigner, J. Grimm, C. Neelsen, J. Jende, S. Orzada, T. Fiedler, S. Kühn, M. Ladd, S. Schmitter
Max Planck Institute for Human Development, Berlin, Germany
Impact: This study demonstrates the potential of a 7 Tesla pTx body array with optimized pTx techniques for imaging the entire spinal cord in a large field of view, paving the way for improved diagnosis of spinal cord pathologies.
16:48 0267. Real-4D parallel transmit pulse design for slab-selective uniform water excitation: demonstration in humans at 7T
X. Shao, Z. Zhang, H. Guo, K. Ugurbil, X. Wu
Tsinghua University, Beijing, China
Impact: Our new design method provides an effective solution for slab-selective uniform water excitation with no out-of-slab fat excitation, holding a promise to many applications including mesoscale fMRI and fat-free body imaging at ultrahigh field.
17:00 0268. Increased intracerebral blood pulsatility as measured with 7T MRI is related to cognitive impairment in a memory clinic sample
M. van der Thiel, M. van den Kerkhof, A. Postma, I. Ramakers, W. Backes, J. Jansen
Maastricht University Medical Center, Maastricht, Netherlands
Impact: This study highlights the clinical value of 7T MRI in measuring small vessel pulsatility and damping, revealing insights into local fluid dynamics and the distinct mechanisms related to cognitive performance in memory clinic patients and healthy controls.
17:12 0269. Whole-brain BOLD Responses to Graded Hypoxic Challenges at 7T, 9.4T, and 15.2T: Implications for Ultrahigh-Field BOLD-DSC MRI
T. T. Le, S. H. Choi, G. H. Im, C. H. Lee, D. Lee, J. Schulman, H. Cho, K. Uludağ, S-G Kim
Center for Neuroscience Imaging Research (CNIR), Institute for Basic Science (IBS), Suwon, Korea, Republic of
Impact: We investigated hypoxia-induced blood and tissue ΔR2* responses across varying ΔY levels and field strengths, alongside CBV assessments. This study provides biophysical insights into field-dependent BOLD signals at ultrahigh fields and addresses challenges in quantification of susceptibility-based CBV measurements.
17:24 0270. Mesoscale T2*-weighted MRI of the human cerebellum at 10.5 Tesla: initial experience
S. Qu, J. de Zwart, P. Van Gelderen, J. Duyn, A. Grant, A. Bratch, E. Auerbach, M. Waks, R. Lagore, L. Delabarre, A. Tarakameh, Y. Eryaman, G. Adriany, K. Ugurbil, G. Oz, X. Wu, J. Liu
CMRR, Radiology, Medical School, University of Minnesota, Minneapolis, United States
Impact: The demonstrated feasibility and utility of motion-robust mesoscale multi- echo EPI in humans at 10.5T may shed light on future optimal implementation of anatomical T2*-weighted cerebellum MRI at ultrahigh field, paving the way for future neuroscience applications.
17:36 0271. In-vivo quantitative histology using 0.36-mm MR Fingerprinting: technical development
X. Cao, A. Beckett, C. Liao, M. Gao, E. Walker, Z. Zhu, A. Kerr, Y. Yang, D. Feinberg, K. Setsompop
Stanford University, Stanford, United States
Impact: This work provides a high-quality, motion-robust, and field-inhomogeneity-robust quantitative tool, enabling whole-brain T1 and T2 maps at 0.36-mm resolution, unprecedented for in-vivo quantitative imaging. It makes in-vivo quantitative histology research feasible, providing possibility to quantitative analysis on fine brain structures.
17:48 0272. Simultaneous T1 and T2 mapping of the brain at 7 Tesla with optimized and accelerated QuantoRAGE
G. Bonanno, T. Nguyên, J. Marques, T. Yu, D. Nickel, B. Açikgöz, J. A. Bastiaansen, R. Kreis, P. Radojewski, B. Maréchal, T. Kober, T. Hilbert
Siemens Healthineers International AG, Bern, Switzerland
Impact:

QuantoRAGE allows for simultaneous T1 and T2 mapping of the whole brain at ultra-high field with high isotropic resolution and in less than 7 minutes, bringing quantitative MRI closer to clinical UHF applications.
18:00   0266. WITHDRAWN
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